Erupción fija medicamentosa debida a loperamida

Matarredona, Jaime; Blasco, Joaquín Borrás; Navarro-Ruiz, A; Devesa, Pedro

doi:10.1157/13071489

Medicina Clínica

2005

DOI: 10.1157/13071489

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Erupción fija medicamentosa debida a loperamida

Jaime Matarredona

Joaquín Borrás Blasco

A Navarro-Ruiz

et al.

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Cited by 2 publications

References 10 publications

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Current awareness: Pharmacoepidemiology and drug safety

2005

Pharmacoepidemiology and Drug

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 20 sections: 1 Books, Reviews & Symposia; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Teratogens/fetal exposure; 20 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Current awareness: Pharmacoepidemiology and drug safety

2005

Pharmacoepidemiology and Drug

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Fixed-drug eruptions: What can we learn from a case series?

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Background:A fixed-drug eruption (FDE) is a unique cutaneous adverse drug effect in the form of recurrent lesions at the same site after re-exposure to the offending agent.Aim:The aim of the study was to identify changes in trends in fixed drug eruptions with regard to causative drug or patient risk factors.Methods:Cases of FDEs encountered between March 2014 to May 2017 during routine pharmacovigilance activities were analyzed.Results:FDEs made up 8.4% of total adverse drug reactions and 11.1% of cutaneous reactions. Majority of the patients were adults between 18 and 45 years old. The average lag period between drug intake and appearance of FDE was 2.04 days. Commonly affected sites were extremities, lips, head and neck, and genitalia. Number of FDE lesions varied from 1 to > 6, with nearly half the patients (46%) presenting with a single lesion. Antimicrobials (80.6%) and nonsteroidal anti-inflammatory drugs (20.8%) were most frequent drugs implicated. Route of administration was oral for all causative drugs. History of an FDE was positive in 26 (50.2%) of the cases. Majority of the patients (21 out of 25 or 84%) whose lesions appeared within minutes to hours of suspected drug intake had a history of FDE. Furthermore, 66.7% of patients with multiple lesions had a history of FDE while only 34.8% of patients with a single lesion had such a history.Conclusion:FDEs are common cutaneous reactions with antimicrobials and anti-inflammatory agents, with increased likelihood of extensive and multiple lesions in patients with a history of FDE.

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Erupción fija medicamentosa debida a loperamida

Cited by 2 publications

References 10 publications

Current awareness: Pharmacoepidemiology and drug safety

Current awareness: Pharmacoepidemiology and drug safety

Fixed-drug eruptions: What can we learn from a case series?

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