2024
DOI: 10.3390/ph17111521
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Eruption Disturbance in Children Receiving Bisphosphonates: Two Case Reports

Tatsuya Akitomo,
Yuko Iwamoto,
Mariko Kametani
et al.

Abstract: Background: Bisphosphonates used for the treatment of osteoporosis, hypercalcemia, or heterotopic calcifications can cause serious adverse dental events such as osteonecrosis of the maxillary and mandibular bones. However, the effects in childhood remain scarcely explored. Case Presentations: We encountered two children who had started bisphosphonate therapy before completion of the primary dentition. No systemic disease causing congenital delayed tooth eruption was diagnosed. Although the children’s height an… Show more

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