CO 2 is now considered as a novel heat transmission fluid to extract geothermal energy. It can achieve both the energy exploitation and CO 2 geological sequestration. The migration pathway and the process of fluid flow within the reservoirs affect significantly a CO 2 plume geothermal (CPG) system. In this study, we built three-dimensional wellbore-reservoir coupled models using geological and geothermal conditions of Qingshankou Formation in Songliao Basin, China. The performance of the CPG system is evaluated in terms of the temperature, CO 2 plume distribution, flow rate of production fluid, heat extraction rate, and storage of CO 2 . For obtaining a deeper understanding of CO 2 -geothermal system under realistic conditions, heterogeneity of reservoir's hydrological properties (in terms of permeability and porosity) is taken into account. Due to the fortissimo mobility of CO 2 , as long as a highly permeable zone exists between the two wells, it is more likely to flow through the highly permeable zone to reach the production well, even though the flow path is longer. The preferential flow shortens circulation time and reduces heat-exchange area, probably leading to early thermal breakthrough, which makes the production fluid temperature decrease rapidly. The analyses of flow dynamics of CO 2 -water fluid and heat may be useful for future design of a CO 2 -based geothermal development system.