Eruption of Permanent Teeth in Mongoloid Children and Their Sibs

Orner, G.

doi:10.1177/00220345730520060701

Cited by 12 publications

(4 citation statements)

References 7 publications

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“…One of the early proposed explanations for the high prevalence of tooth agenesis in individuals with DS was the delayed formation and calcification of tooth germs , introducing false positives into the analysis. In our meta‐analysis, however, studies including children younger than 5 yr of age were excluded for that specific reason.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta‐analysis

Palaska

Antonarakis

2016

European J Oral Sciences

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The aims of the present study were to evaluate the prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome, using meta-analysis methodology. Two independent investigators carried out a literature search to locate articles pertaining to permanent tooth agenesis in individuals with Down syndrome. The outcomes of interest were the prevalence and pattern of permanent tooth agenesis. Thirteen articles were selected for inclusion. The estimated overall prevalence of permanent tooth agenesis, excluding third molars, was 54.6% (95% CI: 44-66%). Considerable heterogeneity was present across the studies. Among subjects with tooth agenesis, approximately half had three or more missing teeth. The permanent teeth with the highest prevalence of agenesis were the maxillary lateral incisor (27%), mandibular second premolar (21%) and maxillary second premolar (18%). The single most commonly absent tooth, however, was the mandibular left second mandibular premolar (19.9%), followed by the maxillary left lateral incisor (19.4%). Little data describing specific tooth-agenesis patterns were available. In conclusion, individuals with Down syndrome display high prevalence rates and severity of agenesis of permanent teeth. Proper and timely diagnosis of missing permanent teeth is thus necessary, to allow a more comprehensive long-term treatment plan and a more favorable prognosis in these individuals.

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Section: Discussionmentioning

confidence: 99%

Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta‐analysis

Palaska

Antonarakis

2016

European J Oral Sciences

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“…Delayed dental development is a recognized clinical manifestation of Down syndrome, the deciduous teeth generally erupting and exfoliating later than in the general population. 12 Agenesis of deciduous teeth occurs in a small percentage of individuals with Down syndrome. 13 However, more often several permanent successor teeth are missing congenitally.…”

Section: Discussionmentioning

confidence: 99%

Tooth Wear in Children with Down Syndrome

Bell

Kaidonis

Townsend

2002

Australian Dental Journal

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Background: Several studies have described the impact that dental caries and periodontitis may have on the dentitions of individuals with Down syndrome, but there are few reports about the effects of tooth wear. This investigation aimed to compare the aetiology, prevalence and severity of tooth wear in 49 cytogenetically confirmed Down syndrome children with 49 non-Down syndrome controls. Methods: This study involved three aspects: an oral examination, including obtaining dental impressions; a dietary analysis spanning three days; and a questionnaire seeking information about habits, medical problems and medications. Tooth wear severity was scored on a 4-grade scale (none-to-little; moderate; severe; very severe), while aetiology was classified as being due to attrition mainly, erosion mainly, or a combination of both. Double determinations established scoring method reliability and chi-square tests assessed associations between samples. Results: Tooth wear was significantly more frequent (p<0.01) in the Down syndrome than the non-Down syndrome sample (67.4 per cent cf 34.7 per cent), with more of the Down syndrome children showing severe to very severe wear (59.2 per cent cf 8.2 per cent). Significantly more Down syndrome children (p<0.05) displayed a multifactorial aetiology of tooth wear, i.e., both attrition and erosion (46.7 per cent cf 28.6 per cent), although no particular dietary link was established. Gastric reflux and vomiting were reported in over 20 per cent of the Down syndrome sample. Conclusions: Given the potential consequences of high levels of tooth wear, associated with tooth grinding and an acidic oral environment in Down syndrome children, educational programmes aimed at increasing awareness of carers and health professionals are needed urgently.

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“…Congenital and acquired diseases such as DS can alter the indices concerning such assessment. DS individuals might present different clinical characteristics [27,28], such as delayed teeth eruption in both, deciduous and permanent dentitions, a condition that might also affect non-DS individuals [29,30].…”

Section: Discussionmentioning

confidence: 99%

Comparison of accuracy between dental and skeletal age in the estimation of chronological age of Down syndrome individuals

Hala

Moraes

Villaça-Carvalho

et al. 2016

Forensic Science International

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This study aimed to evaluate the accuracy of dental age (DA) and skeletal age (SA) methods in order to estimate chronological age (CA) in individuals with Down syndrome (DS), contributing to the Forensic Dentistry and making the identification of these individuals age possible. For this, 278 images of individuals were selected and divided in 2 groups: 216 non-DS patients and 62 with DS. At first, DA was evaluated by Nolla method, on panoramic radiographs, followed by SA, evaluated by Greulich and Pyle method. The linear correlation coefficient of Pearson was used for the analysis of concordance between the methods. Paired t-test with confidence interval was used to evaluate the accuracy and Bland and Altman method was applied to estimate limits of concordance. Complementary to this first analysis, descriptive statistics and ANOVA test were applied for comparison among chronological age (CA), dental age (DA) and skeletal age (SA), with a significance level of 95% (p≥0.05), ordering to observe the differences among them. DA, estimated by Nolla, is underestimated in both, DS and non-DS individuals, and it is more notable in DS individuals. SA estimated by Greulich and Pyle method is overestimated, except for non-DS males. The range of variance is greater in SA and DS than DA and non-DS individuals, respectively. A greater accordance was found for DA×CA if compared to SA×CA, indicating that DA, estimated by Nolla method, is more accurate than SA, evaluated by Greulich and Pyle method, for estimating CA of both, DS and non-DS individuals. However, neither method seems to be precise and more caution is required for age estimation in DS individuals.

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Eruption of Permanent Teeth in Mongoloid Children and Their Sibs

Cited by 12 publications

References 7 publications

Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta‐analysis

Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta‐analysis

Tooth Wear in Children with Down Syndrome

Comparison of accuracy between dental and skeletal age in the estimation of chronological age of Down syndrome individuals

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