2011
DOI: 10.1111/j.1346-8138.2011.01332.x
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Eruptive disseminated porokeratosis following bone marrow transplantation for acute lymphoblastic leukemia in a child

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Cited by 12 publications
(12 citation statements)
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“…The most commonly affected population is middle‐aged patients with a history of solid organ transplantation; lesions typically develop 3 to 4 years after transplantation . The youngest case previously reported of eruptive disseminated porokeratoses was a 13‐year‐old Peruvian boy who had undergone bone marrow transplantation for acute lymphocytic leukemia . Ours is the youngest reported case of disseminated superficial porokeratoses, having developed at the age of 3 years, and only the second with lesions on the face.…”
Section: Discussionmentioning
confidence: 99%
“…The most commonly affected population is middle‐aged patients with a history of solid organ transplantation; lesions typically develop 3 to 4 years after transplantation . The youngest case previously reported of eruptive disseminated porokeratoses was a 13‐year‐old Peruvian boy who had undergone bone marrow transplantation for acute lymphocytic leukemia . Ours is the youngest reported case of disseminated superficial porokeratoses, having developed at the age of 3 years, and only the second with lesions on the face.…”
Section: Discussionmentioning
confidence: 99%
“…This relationship is more common in patients in their fourth decade of life, appearing 3.5 years after organ transplant . To our knowledge, only 20 cases of porokeratosis have been reported associated with bone marrow transplantation, two of them in children (Table ) . These have been cases of disseminated porokeratosis triggered by immunosuppression and treated with urea and acitretin.…”
Section: Discussionmentioning
confidence: 99%
“…suggested EDP as a new variant of porokeratosis that clinically resembles DSP with a similar distribution of lesions but with a different time evolution. EDP has previously been described in patients with cancer of the liver, colon and pancreas, and also with organ transplant, diabetes mellitus, herpes simplex infection, bone marrow transplant, myelodysplastic syndrome, and both immunosuppressant and nonimmunosuppressant drug therapy. Only one other case of EDP directly attributable to systemic corticosteroid immunosuppression, which was a 75‐year‐old man treated with betamethasone for DSP, has been reported previously.…”
Section: Reportmentioning
confidence: 92%
“…Porokeratosis lesions result from the peripheral expansion of an abnormal mutant clone of epidermal keratinocytes, which may be triggered by light, trauma, infection or immunosuppression . The DSP variant is seen most often in immunosuppressed patients, typically appearing symmetrically on the limbs and less often on the trunk …”
mentioning
confidence: 99%
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