Eruptive disseminated superficial actinic porokeratosis in an immunocompetent host: Is this associated with herpes simplex virus or bacterial infection?

Disseminated Inflammatory Lesions in 2 Patients With COVID-19: Answer

“…Viral infections such as herpes simplex, hepatitis C, and HIV infection are also known to contribute to the onset and to the inflammatory exacerbations of porokeratoses. 6,7 In the first case, the patient's medical history and the presence of lesions with ridge-like borders were consistent with the diagnosis of DSP. The histopathological examination revealed a cornoid lamella next to a hair follicle, with focal involvement of its wall.…”

“…Viral infections such as herpes simplex, hepatitis C, and HIV infection are also known to contribute to the onset and to the inflammatory exacerbations of porokeratoses. 6,7…”

A case of bullous eruptive disseminated porokeratosis

“…In some patients, the presence of pre‐existing porokeratoses was noted, and dissemination appeared to represent an inflammatory flare, which was not the case here. Finally, although this patient's lesional PCR was negative, HSV has been reported as a possible trigger of acute‐onset DSAP …”

Porokeratoses—A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants

“…Rarely, DSAP develops bullous [28] or prurigo nodularis-like forms [29]. There are reports of non-actinic DSAP in immunocompromised patients (organ transplant recipients, oncological patients, HIV-positive patients and others) [28,[30][31][32][33][34][35][36][37], pyoderma gangrenosum [34], pseudoxanthoma elasticum [38], dermatomyositis [39], systemic scleroderma [40], Sjögren's syndrome [41], in combination with glioblastoma and Lynch syndrome [42] and during hydroxyurea treatment [43,44].…”