Eruptive vellus hair cyst and steatocystoma multiplex: two related conditions?

Sánchez-Yus, E; Aguilar-Martínez, Antonio; Cristóbal‐Gil, M. C.; Urbina‐González, F.; Guerra‐Rodríguez, P.

doi:10.1111/j.1600-0560.1988.tb00514.x

Cited by 48 publications

(30 citation statements)

References 19 publications

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“…The biopsies of the mother’s cysts revealed the typical features of steatocystoma in the biopsy taken from one of the larger cysts located in the trunk and features of EVHC in the biopsy taken from one of the cysts of the face. The association of a sebaceous gland near the cyst, as observed in this case, has previously been described in EVHC [7], but some authors have suggested that cysts with these histopathologic features might be considered ‘hybrid cysts’ with features of both SM and EVHC [8, 9, 10, 11]. …”

Section: Discussionmentioning

confidence: 87%

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

et al. 1998

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Background: Steatocystoma multiplex (SM) and eruptive vellus hair cysts (EVHC) are conditions characterized by numerous cutaneous cysts with a clinical resemblance, such as age of onset, location, appearance of the lesions and mode of inheritance, but with distinctive histologic features. Recently, some authors have proposed that the two conditions are variants of one entity originating in the pilosebaceous duct, while others suggest that SM and EVHC are two distinct entities, on the basis of the different expression of keratins. Milia are small round cysts, commonly involving the face. In 1994, Menni and Piccinno reported the first association, in a family, between persistent infantile milia in a 9-month-old girl and SM in the father. The authors hypothesized a relationship between these two conditions. Objective: We describe a family in which the mother showed cystic lesions and milia and her 4-year-old son and her 18-month-old daughter presented persistant infantile milia. Methods: In addition to the clinical and genetic documentation, a biopsy was performed in the son and two biopsies in the mother. Results: The histologic examination of one of the son’s milium-like papules showed in the superficial dermis a small cyst typical of a milium. In serial sections it was possible to see a connection with a vellus hair follicle by an epithelial pedicle. The histologic examination of one of the mother’s papules on the forehead showed a large round cystic structure with histologic features of EVHC. Close to the cyst wall, serial sections showed flattened sebaceous gland lobules. The histologic findings of the second biopsy taken from the chest showed the typical features of a steatocystoma. Conclusions: The relationship between milia, SM and EVHC is discussed; the three diseases should be considered as subtypes of multiple pilosebaceous cysts that may all present overlapping histologic features. The different level of the pilosebaceous duct where the cyst originates should explain the different clinical manifestations.

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Section: Discussionmentioning

confidence: 87%

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

et al. 1998

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“…EVHC mostly develop as a consequence of occlusion of the infundibulum of vellus hairs with resultant cystic dilatation and retention of keratinous debris and vellus hairs. The characteristic histology is that of a mid-dermal cyst containing laminated keratin and many vellus hairs 4 . Although milia and EVHC are distinct from one another, in our case, milia and EVHC were revealed Pilosebaceous Cysts with Apocrine Hidrocystoma: Same Disease Process?…”

Section: Discussionmentioning

confidence: 99%

Two Pilosebaceous Cysts with Apocrine Hidrocystoma in One Biopsy Site: A Spectrum of the Same Disease Process?

Hwang

Cho

et al. 2008

Ann Dermatol

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A 28-year-old woman presented with multiple, asymptomatic, erythematous to bluish papules located on the chest. Histopathologically, three round, well defined cystic structures were seen on the upper and lower dermis. The first cyst was milia, the second was apocrine hidrocystoma and the other, largest cyst was an eruptive vellus hair cyst (EVHC). A diagnosis of multiple pilosebaceous cysts combined with apocrine hidrocystoma was made. Since the milia and EVHC originate from the pilosebaceous unit, and the apocrine duct opens to the pilosebaceous orifice, we suggest that they can occur simultaneously in the same unit. (Ann Dermatol (Seoul) 20(1) 11∼13, 2008)

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“…Steffen and Ackerman |24| stated that'we do not consider eruptive hair cyst to be an entity sui generis or a hybrid but simply a steatocystoma', that the cystic formations in the patients examined by Urbina González et al [6], Sánchez et al [7], Sexton and Mur dock [9] and Requena and Sánchez Yus [23] are 'just alluded to as steatocystoma alone.…”

Section: Discussionmentioning

confidence: 99%

“…a clinically similar but histologically different entity, was first men tioned in 1977 15 1. Recently, several reports have presumed that at least in some patients both cysts can be seen or that the cysts may show histological features of both cysts [6][7][8][9][10], We describe a female patient who showed both types of cysts within one lesion. …”

Section: Introductionmentioning

confidence: 99%

Eruptive Vellus Hair Cyst and Steatocystoma multiplex: Hybrid Cysts

Hürlimann¹,

Panizzon²,

Burg³

1996

Dermatology

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Steatocystoma multiplex (SM) and eruptive vellus hair cyst (EVHC) are known as clinically similar but histologically distinct entities, first described by Jamieson in 1873 and Esterly et al. in 1977, respectively. Herein we describe a 24-year-old female patient with both lesions on the anterior chest wall. The biopsy showed portions of two cysts close together with features of SM in one part and features of EVHC in the other part. Our case gives further evidence that these two conditions are closely related. To the best of our knowledge this is the first case where such an anatomically close relationship between these two types of cysts has been described.

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Eruptive vellus hair cyst and steatocystoma multiplex: two related conditions?

Cited by 48 publications

References 19 publications

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

Two Pilosebaceous Cysts with Apocrine Hidrocystoma in One Biopsy Site: A Spectrum of the Same Disease Process?

Eruptive Vellus Hair Cyst and Steatocystoma multiplex: Hybrid Cysts

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