Erythema Ab Igne Successfully Treated With Mesoglycan and Bioflavonoids: A Case-Report

Abstract

Erythema ab igne is a localised, cutaneous condition consisting of reticulate hyperpigmentation, epidermal atrophy, and telangiectasias. It is caused by repetitive and prolonged exposure to moderate heat that is insufficient for producing burns. Currently, erythema ab igne is most commonly observed following repeated use of hot water bottles, infrared lamps and heating pads. If not properly treated, erythema ab igne can become chronic and even malignant. We report a case of erythema ab igne, successfully treated with systemic mesoglycan-based therapy, and local therapy with bioflavonoids.

Erythema Ab Igne: A Rare Presentation of Toasted Skin Syndrome With the Use of a Space Heater

“…The histopathological changes include epidermal atrophy, hyperkeratosis and parakeratosis, liquefactive degeneration of the basal layer, melanin and hemosiderin deposition, and the formation of telangiectasias. The dermis shows melanophages and isolated elastic fiber alterations similar to actinic elastosis, which is usually seen with prolonged sun exposure [ 4 ]. A rare variant includes crusting bullous lesions overlying the reticular rash.…”

“…The pathophysiology does not seem to be fully understood and multiple mechanisms have been proposed, including the repeated heat exposure damaging superficial blood vessels leading to hemosiderin deposition and subsequent hyperpigmentation. Additionally, the release of melanin from heat-induced damage to elastic fibers and basal cells imparts the characteristic reticular rash in a vascular pattern [ 4 ]. While it usually resolves in weeks to months after the removal of the heat source, the rash has a propensity to become permanent, and in some cases, transforms into cutaneous malignancies [ 5 - 7 ].…”

Clinical features and etiology of patients with erythema ab igne: A retrospective multicenter study

“…Regular skin examinations are recommended if there is suspicion of epidermal atypia. Topical fluorouracil (5‐FU) or imiquimod therapy is recommended if epithelial atypia is present . Patients with ulceration, bullae, and persistent lesion should be monitored for possible malignant transformation, as these lesions may cause development of squamous cell carcinoma and Merkel cell carcinoma.…”