Erythema annulare centrifugum and Escherichia coli urinary infection

Borbujo, J.; Miguel, C. de; Lopez, A.C.; Lucas, R. de; Casado, María Bustillo

doi:10.1016/s0140-6736(96)91374-4

Cited by 14 publications

(7 citation statements)

References 4 publications

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“…However, there have been reports of EAC in association with many conditions, such as infections (bacterial, viral, or fungal), drugs, malignant neoplasms, hormonal abnormalities, parasitic infestation and other systemic diseases. The infectious etiology included dermatophytes, particularly present as tinea pedis, Epstein‐Barr virus, molluscum contagiosum, Escherichia coli , and Candida albicans (4–7). Among these, dermatophyte infection is known to be the most important cause of EAC (3, 8).…”

Section: Discussionmentioning

confidence: 99%

Clinicopathologic Analysis of 66 Cases of Erythema Annulare Centrifugum

Kim

Chang

Choi

et al. 2002

The Journal of Dermatology

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Erythema annulare centrifugum (EAC) denotes a group of eruptions characterized by slowly migrating annular or configurate erythematous lesions. It can be classified histopathologically as the deep or superficial type. Although there are many case reports of EAC associated with various underlying conditions, no recent clinicopathologic studies exist. The purpose of this study was aimed at analyzing the clinical and histopathologic features of EAC. Sixty-six patients who have been diagnosed as EAC by clinical and histopathological examination were collected. The medical records and skin biopsy specimens of these patients were reviewed retrospectively. There were 24 male patients and 42 female ones. The mean age was 39.7 years, and the mean durtion of the disease was 2.8 years. The lower extremities, particularly the thigh, were the most frequently involved locations. The most common clinical manifestation was large (>1 cm), scaly, erythematous, indurated plaques. Forty-eight patients (72%) had combined diseases including cutaneous fungal infection (48%), such as tinea pedis, other skin diseases (18%), internal malignancies (13%), and other systemic diseases (21%). By histopathologic examination, 33 of 42 patients (78%) were identified as superficial type, and 9 patients (22%) were deep type. Therapeutic trials with systemic or topical corticosteroid and oral antihistamine did not affect the chronic and recurrent course of these patients. EAC is a chronic and recurrent disease despite treatment. EAC is thought to be highly associated with internal disease as well as with superificial fungal infection. However, it was difficult to prove a causal association. The recognition and exact diagnosis of EAC is important, because it may be a quite stressful condition and lead to unnecessary over-treatments.

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Section: Discussionmentioning

confidence: 99%

Clinicopathologic Analysis of 66 Cases of Erythema Annulare Centrifugum

Kim

Chang

Choi

et al. 2002

The Journal of Dermatology

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“…EAC does not show predilection for sex, and pick of incidence is between 30 and 50 years of life. EAC is considered a reactive dermatosis 3,4 and bacterial, fungal and viral antigens, drugs, neoplasm, autoimmune diseases have been described as possible causative factors, [5][6][7][8][9][10][11][12][13][14][15][16][17][18] nevertheless in the majority of cases, the aetiology remains unexplained. 19 Histologically, EAC is characterized by a subacute inflammatory process with lymphocytes and occasional eosinophils around the blood vessels of the upper dermis.…”

Section: Introductionmentioning

confidence: 99%

Erythema annulare centrifugum: report of a case with neonatal onset

Bottoni

Innocenzi

Bonaccorsi

et al. 2002

Acad Dermatol Venereol

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Darier's erythema annulare centrifugum (EAC) is often associated with infectious, autoimmune or neoplastic disease, nevertheless, most cases of EAC remain unexplained. We report a case of EAC with neonatal onset and a clinical course of over 20 years. The patient presented from the 6th day of life with erythematous papules that enlarged centrifugally to form figurate, annular or policyclic plaques involving the entire cutaneous surface. The clinical picture had a chronic course, disappearing only during unrelated febrile episodes. Histologic examination revealed a normal epidermis and a dense perivascular lymphohistiocytic infiltrate and numerous eosinophils in the superficial and reticular dermis. Today the patient is 24 years old and his lesions are still unchanged. Recently, clinical evaluation revealed a diffuse sderodermic induration. A second biopsy showed a diffuse thickening of collagen fibers in the dermis. To our knowledge, this is the second report of EAC with neonatal onset and such a long and peculiar clinical course.

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“…However it is considered to be a hypersensitivity reaction to bacterial, viral, mycobacterial, parasitic or fungal infections, drugs (salicylates and antimalarials) or malignancy (tumor proteins). It has also been reported in association with autoimmune disorders, thyroid diseases, menstruation and ingestion of blue cheese (3,4). The gastrointestinal disorders reported in association with EAC are acute appendicitis, liver disease and cholecystitis (5,6).…”

Section: Discussionmentioning

confidence: 98%