Erythema annulare centrifugum as the presenting sign of breast carcinoma

Panasiti, Vincenzo; Devirgiliis, Valeria; Curzio, Michela; Roberti, Vincenzo; Bottoni, Ugo; Calvieri, Stefano

doi:10.1111/j.1468-3083.2008.02848.x

Cited by 15 publications

(9 citation statements)

References 7 publications

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“…Paraneoplastic EAC has been described as the presenting sign of breast cancer and also after surgery for breast cancer . In these patients, annular skin lesions have a predilection for the trunk and legs, and the histopathology shows epidermal spongiosis and superficial perivascular lymphocytic infiltrates.…”

Section: Reportmentioning

confidence: 99%

Cutaneous metastasis of inflammatory breast carcinoma mimicking an erythema annulare centrifugum: a sign of locally recurrent cancer

et al. 2016

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SummaryErythema annulare centrifugum (EAC) is a clinical reaction pattern that includes lupus erythematosus, spongiotic dermatitis (particularly pityriasis rosea), pseudolymphoma and cutaneous B-cell lymphoma. However, it can be the result of cutaneous metastasis by an internal carcinoma. We present the case of a 38-year-old woman with bilateral inflammatory breast cancer following multimodal therapy. After chemotherapy, the patient developed EAC on her back, clinically suspect of subacute cutaneous lupus erythematosus. A skin biopsy of annular lesion revealed dermal lymphatic infiltration by inflammatory breast carcinoma. Immunohistochemically, HER2 overexpression and negativity for hormone receptor are the hallmarks of this disease. Cutaneous metastasis by inflammatory breast carcinoma mimicking EAC is rare, and it has not been described in extramammary locations. Its recognition by the dermatologist is important because it can be a clinical manifestation of locally recurrent cancer.Inflammatory carcinoma or carcinoma erysipelatodes is a rare form of cutaneous metastasis by an internal carcinoma located in the superficial lymphatic system.

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Section: Reportmentioning

confidence: 99%

Cutaneous metastasis of inflammatory breast carcinoma mimicking an erythema annulare centrifugum: a sign of locally recurrent cancer

et al. 2016

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“…Solid tümörler Ekinci ve ark. Paraneoplastik özellik gösteren reaktif dermatozlar ise akciğer kanseri (5 olgu), meme kanseri (2 olgu), gastrointestinal kanserler (3 olgu), prostat kanseri (2 olgu), peritoneal kanser (1 olgu), nazofarengeal kanser (1 olgu) ve karsinoid tümör (1 olgu) olarak belirtilmiştir 22,[33][34][35][36][37][38] . Bu 40 olgunun yaş ortalaması 55 olup %64'ü kadındır.…”

Section: Eritem Anüler Santrifüjunclassified

Paraneoplastik özellik gösteren reaktif dermatozlar

Ekinci¹,

Aslan²

2013

TURKDERM

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ÖzetReaktif dermatozlar infeksiyonlar, inflamatuar hastalıklar, ilaç kullanımı ve maligniteler başta olmak üzere birçok nedenle ortaya çıkabilirler. Böyle bir dermatozla karşılaşan hekimler dermatozu tedavi etmenin yanı sıra altta yatan nedeni araştırmaya da yönelirler. Bu derlemede, reaktif dermatozların paraneoplastik potansiyelleri değerlendirilerek tanı sonrası etyoloji, takip ve tedavide yapılması gerekenler irdelenmiştir. Sum maryReactive dermatoses may occur related to many underlying causes including infections, inflammatory diseases, medications and malignancies. In the management of these dermatoses the investigation of underlying cause is crucial besides the therapy of dermatosis. In this review, mainly the paraneoplastic potentials of reactive dermatoses have been evaluated and additionally the etiology, follow-up and treatment have been discussed. Recent literature about figurated erythemas (erythema annulare centrifugum, erythema gyratum repens, necrolytic migratory erythema), neutrophilic dermatoses (Sweet's syndrome, pyoderma gangrenosum, subcorneal pustular dermatosis) and erythema nodosum have been scrutinized. (Turkderm 2013; 47: Suppl 2: 69-77) Key Words: Paraneoplasia, reactive dermatoses, Sweet syndrome, erythema gyratum repens, necrolytic migratory erythema, erythema annulare centrifugum, subcorneal pustular dermatosis, erythema nodosum, pyoderma gangrenosum

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“…Some reports of malignancy-associated EAC have been presented. According to the reports, EAC is related with solid and hematologic malignancies such as breast cancer, leukemia, and lymphoma2,3. Histopathologically, it is characterized by perivascular tightly cuffed 'coat-sleeve-like' lymphohistiocytic infiltrates.…”

mentioning

confidence: 99%