Erythema Annulare Centrifugum Associated with Mantle B-cell Non-Hodgkin's Lymphoma

Carlesimo, Marta; Fidanza, Laura; Mari, Elena; Pranteda, Guglielmo; Cacchi, Claudio; Veggia, Barbara; Cox, Maria Christina; Camplone, G.

doi:10.2340/00015555-0615

Cited by 19 publications

(11 citation statements)

References 3 publications

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“…Aetiopathogenesis of erythema annulare centrifugum is still unknown, but it is associated with many conditions such as infections, food and drug assumptions, endocrinological disorders and malignant neoplasms . We described a patient in which recurrent erythema annulare centrifugum was diagnosed 2 years before the onset of a B NHL, and only another similar case has been described in literature (Fig. ).…”

Section: Non‐specific Lesionsmentioning

confidence: 99%

Cutaneous manifestations of systemic non‐Hodgkin lymphomas (NHL): study and review of literature

Carlesimo¹,

Narcisi²,

Rossi

et al. 2013

Acad Dermatol Venereol

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Systemic non-Hodgkin lymphomas are often accompanied by cutaneous manifestations, which are not always looked out for. Nevertheless, these alterations can be very important because their presence is lied to the clinical behaviour of the underlying malignancy, with an early recognition being fundamental. The aim of this study was to make order in this topic and propose a preliminary classification of the cutaneous manifestations associated with non-Hodgkin lymphomas. We performed a retrospective chart review of 62 haematological patients affected by non-Hodgkin systemic lymphomas with dermatological manifestations, who were evaluated from January 2007 to December 2011, and combined these results with a systematic review of Pub medical literature from 1937 to 2011 on this topic. A preliminary classification of these manifestations has been proposed, dividing them in specific and non-specific ones, along with a description of the clinical features and those cases observed in our department. A preliminary approach has been proposed for the study of these manifestations that could be helpful in understanding the biological behaviour and aid early recognition of a flare up in systemic non-Hodgkin lymphomas.

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Section: Non‐specific Lesionsmentioning

confidence: 99%

Cutaneous manifestations of systemic non‐Hodgkin lymphomas (NHL): study and review of literature

Carlesimo¹,

Narcisi²,

Rossi

et al. 2013

Acad Dermatol Venereol

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“…Bu neoplazilerin %62,5'inin lenfoproliferatif, %37,5'inin solid tümörler olduğu belirtilmiştir 22 . Lösemi ve lenfoma 11'er hastada saptanarak EAS ile en sık ilişkili maligniteler olarak tanımlanmışlardır 22,[26][27][28][29][30][31][32] . Solid tümörler Ekinci ve ark.…”

Section: Eritem Anüler Santrifüjunclassified

Paraneoplastik özellik gösteren reaktif dermatozlar

Ekinci¹,

Aslan²

2013

TURKDERM

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ÖzetReaktif dermatozlar infeksiyonlar, inflamatuar hastalıklar, ilaç kullanımı ve maligniteler başta olmak üzere birçok nedenle ortaya çıkabilirler. Böyle bir dermatozla karşılaşan hekimler dermatozu tedavi etmenin yanı sıra altta yatan nedeni araştırmaya da yönelirler. Bu derlemede, reaktif dermatozların paraneoplastik potansiyelleri değerlendirilerek tanı sonrası etyoloji, takip ve tedavide yapılması gerekenler irdelenmiştir. Sum maryReactive dermatoses may occur related to many underlying causes including infections, inflammatory diseases, medications and malignancies. In the management of these dermatoses the investigation of underlying cause is crucial besides the therapy of dermatosis. In this review, mainly the paraneoplastic potentials of reactive dermatoses have been evaluated and additionally the etiology, follow-up and treatment have been discussed. Recent literature about figurated erythemas (erythema annulare centrifugum, erythema gyratum repens, necrolytic migratory erythema), neutrophilic dermatoses (Sweet's syndrome, pyoderma gangrenosum, subcorneal pustular dermatosis) and erythema nodosum have been scrutinized. (Turkderm 2013; 47: Suppl 2: 69-77) Key Words: Paraneoplasia, reactive dermatoses, Sweet syndrome, erythema gyratum repens, necrolytic migratory erythema, erythema annulare centrifugum, subcorneal pustular dermatosis, erythema nodosum, pyoderma gangrenosum

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“…Lesions tend to appear on the trunk, proximal parts of the extremities and, more frequently, in the superficial type appear especially on the buttocks [2].This is a chronic and recurrent…”

Section: Conflict Of Interest Statementmentioning

confidence: 99%

“…EAC was first described by Darier in 1916, and classified in 1978 by Ackerman into a superficial and a deep type [1]. EAC has been associated with many different entities, including infections, food allergy and drug reactions, polycythemia vera, cryoglobulinaemia, myelodysplastic syndrome, hypereosinophilic syndrome, hyperthyroidism, autoimmune thyroidities, hepatic diseases, pregnancy and malignant neoplasms [2]. Relapsing polychondritis (RP) is a disease which progresses with inflammatory attacks on articular and non-articular cartilaginous tissue and is most commonly encountered as auricular chondritis.…”

mentioning

confidence: 99%

Erythema Annulare Centrifugum and Relapsing Polychondritis Associated with Acute Myeloid Leukemia: A Case Report

Toprak¹,

Karakuş²,

Halacoglu³

et al. 2012

Turk J Hematol

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Erythema annulare centrifugum (EAC) is a slow progressing and recurring skin disease with unknown etiology, characterized by ring shaped erythematous skin rashes. EAC was first described by Darier in 1916, and classified in 1978 by Ackerman into a superficial and a deep type [1]. EAC has been associated with many different entities, including infections, food allergy and drug reactions, polycythemia vera, cryoglobulinaemia, myelodysplastic syndrome, hypereosinophilic syndrome, hyperthyroidism, autoimmune thyroidities, hepatic diseases, pregnancy and malignant neoplasms [2]. Relapsing polychondritis (RP) is a disease which progresses with inflammatory attacks on articular and non-articular cartilaginous tissue and is most commonly encountered as auricular chondritis. In auricular chondritis, that the earlobe is not affected and existence of one or two sided fulminant rubescence, sensitivity and oedema on external ear cartilaginous tissue are salient [3]. We report a case, who was diagnosed with acute myeloblastic leukemia (AML) two months after EAC was detected. Bilateral auricular chondritis developed in the third day of her chemotherapy and EAC lesions relapsed during the course of chemotherapy.A 53 year old female patient with complaints of a sore throat was assessed in otorhinolaryngology polyclinic.While diagnosed with tonsillitis and her antibiotherapy arranged, she was redirected to us upon detection of anemia, moderate thrombocytopenia and leukocytosis (hemoglobin 11.2 g/dL, hematocrit 33%, mean corpuscular volume 91 fL, white blood cell 19.2 x 10 9 /L, neutrophile 0.9 x 10 9 /L, thrombocyte 120 x 10 9 /L). In her physical examination no symptom was found except cryptic tonsillitis. She did not have a known systemic disease nor she did regularly use a medication. Her liver, kidney and thyroid functions tests were normal. In her bone marrow biopsy, conducted upon monitoring of blastic cell with a rate of 90% during her peripheral smear, diffuse blastic cell infiltration was found. In bone marrow aspiration, usually large, potential undifferentiated blasts with heterogenous structure and agranular cytoplasm, but not involving Auer rods, were detected. After immunohistochemical examination the patient was diagnosed with AML M0, and classic 7+3 induction chemotherapy regimen involving cytosine arabinoside and idarubicin combination protocol was initiated. On the third day of treatment palpable rash on her abdominal skin (Figure 1), and swelling, rubescence and sensitivity on both ears that do not prominently effect the earlobe (Figure 2a -2b) occurred. A biopsy from the lesions on the abdominal skin was performed. Lesions on the ear auricle of the patient were assessed as

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Erythema Annulare Centrifugum Associated with Mantle B-cell Non-Hodgkin's Lymphoma

Abstract: [No abstract available

Cited by 19 publications

References 3 publications

Cutaneous manifestations of systemic non‐Hodgkin lymphomas (NHL): study and review of literature

Cutaneous manifestations of systemic non‐Hodgkin lymphomas (NHL): study and review of literature

Paraneoplastik özellik gösteren reaktif dermatozlar

Erythema Annulare Centrifugum and Relapsing Polychondritis Associated with Acute Myeloid Leukemia: A Case Report

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