Erythema Dyschromicum Perstans: A Case Report

Durmaz, Koray; Özer, İlkay; Fındık, Sıddıka; Oltulu, Pembe; Ataseven, Arzu

doi:10.4172/2376-0427.1000266

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…But for many patients however, longstanding EDP can be chronically disfiguring and a disconcerting problem that is resistant to treatment modalities. [6] Clinicians should suspect this entity whenever a large pigmentary process is presented so that therapy can be initiated much earlier and lessen the residual impact of the lesions.…”

Section: Discussionmentioning

confidence: 99%

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Erythema Dyschromicum Perstans: The Spotty Possibility – A Rare Case Report

Lochini

Nilofer

Lilly

2021

JPRI

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Erythema Dyschromicum Perstans (EDP) / Ashy Dermatosis are a less common dermatological disorder with an unknown etiology. It is characterized by asymptomatic, grey, symmetric and confluent macules all over the body. Herein, we report a case of a 50 years old man who presented clinically, with diffuse, patchy pigmentation having ill-defined, erythematous borders involving bilateral arms and forearms. Histopathological examination of the lesion biopsy demonstrates vacuolar degeneration of the basal cell layer, dermal perivascular mononuclear cell infiltrate and increased epidermal melanin pigment and presence of dermal melanophages. For the present case, treatment with Clofazimine has proven to be effective.

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Section: Discussionmentioning

confidence: 99%

“…Use of various therapies including topical and systemic corticosteroids, UV light, antimalarial agent and antibiotics has been reported without clear evidence of benefit [5,6]. Some limited data from small studies suggest significant benefit from treatment with Clofazimine [7,8].…”

Section: Differential Diagnosis Of This Condition Includesmentioning

confidence: 99%

Erythema Dyschromicum Perstans: The Spotty Possibility – A Rare Case Report

Lochini

Nilofer

Lilly

2021

JPRI

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Ashy Dermatosis: Suatu Laporan Kasus Jarang

Fatimah Fitriani,

Moerbono Mochtar

2024

MEDICINUS

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Background: Ashy dermatosis is a rare, acquired, benign, and idiopathic hypermelanotic disease. It is manifested asashy-colored lesion with no signs of inflammation. Commonly affected sites of the body include the trunk, neck, face, also proximal and distal extremities. Case: A 33-year-old woman came to Dr. Moewardi Hospital, Surakarta, with chief complaints asymptomatic, ashy colored macule that appear on her right arm. Physical examination in general region shows ashy-colored macule and multiple discrete patches of hyperpigmentation with irregular border. Dermoscopy examinationmacules showed bluish-gray skin markings over bluish background. Histopathological examination showed thin epidermis layer, hyperkeratosis, incontinentia pigmenti, dropping melanin resembles the basal layer civatte bodies. At dermis focal fibrosis was found with infiltrates, incontinentia pigmenti, and dropping melanin. Discussion: Ashy dermatosis or known as erythema dyschromicum perstans is a rare hyperpigmentation disorder that started with reddish, active-bordered lesions, then disappear, leaving a round or oval shape, polycyclic, and ashy macule on the proximal region of the trunk andneck. Onset of symptoms usually at young adult, between first and second decade of life. Etiology of ashy dermatosis is still unclear, and many factors were thought to be involved. Dermoscopy examination showed bluish-gray macules overbluish background. Histopathological examination showed lichenoid reactions and an increase melanin on the dermis. This report aims to describe the diagnosis a rare condition based on anamnesis, physical examination, dermoscopy, and histopathological examination. Clinical findings in this patient were in accordance with the result of previous studies.

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Erythema Dyschromicum Perstans: A Case Report

Cited by 2 publications

References 6 publications

Erythema Dyschromicum Perstans: The Spotty Possibility – A Rare Case Report

Erythema Dyschromicum Perstans: The Spotty Possibility – A Rare Case Report

Ashy Dermatosis: Suatu Laporan Kasus Jarang

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