Erythema elevatum diutinum in systemic lupus erythematosus

Chan, Yung; Mok, Chi Chiu; Tang, William

doi:10.1007/s00296-010-1574-3

Cited by 11 publications

(8 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Bullous skin lesions, refractory to prednisolone, were partially relieved with the introduction of dapsone in 1 patient with methimazole-induced bullous SLE [28]. Chan et al [29] reported successful treatment with 50 mg of dapsone for erythema elevatum diutinum in connection with SLE; the skin lesions were markedly improved after a few weeks. …”

Section: Discussionmentioning

confidence: 99%

Dapsone as Second-Line Treatment for Cutaneous Lupus Erythematosus? A Retrospective Analysis of 34 Patients and a Review of the Literature

2015

View full text Add to dashboard Cite

Background: A variety of therapeutic options have been reported for cutaneous lupus erythematosus (CLE); one of these is dapsone. However, no high priority has been given to this drug. Objective: To determine whether dapsone is an effective and safe treatment alternative in patients with LE. Methods: We reviewed the literature and analyzed retrospectively 34 CLE patients who were treated with dapsone as monotherapy or combined with antimalarials. We assessed the course of the disease under treatment, response, concomitant treatment and side effects. Results: Six patients went into remission, 14 patients improved, and in 6 patients disease remained constant during the observation period. Dapsone was discontinued in 9 patients: in 4 due to reversible side effects and in 5 patients due to poor efficacy. Conclusion: Our data confirm that dapsone with/without antimalarials is effective in more than 50% of patients with CLE and could be used as second-line therapy for CLE.

show abstract

Section: Discussionmentioning

confidence: 99%

Dapsone as Second-Line Treatment for Cutaneous Lupus Erythematosus? A Retrospective Analysis of 34 Patients and a Review of the Literature

2015

View full text Add to dashboard Cite

show abstract

“…Other associations include relapsing polychondritis ( n = 1), Wegener's granulomatosis ( n = 1), arthridities ( n = 3), connective tissue disorders ( n = 3), dermatomyositis ( n = 1) and inflammatory bowel disease ( n = 2) . Elsner et al .…”

Section: Eed and Associationsmentioning

confidence: 99%

Erythema elevatum diutinum: a review of presentation and treatment

Momen

Jorizzo

Al‐Niaimi

2014

Acad Dermatol Venereol

View full text Add to dashboard Cite

Erythema elevatum diutinum (EED) is a rare, chronic and treatable skin condition. It has many histological mimics and is often associated with a variety of underlying systemic diseases, when these are present the management and prognosis dictates the course of the EED. This review aims to highlight the differential diagnosis, clinical manifestations of EED and the possible underlying systemic disease. It is important for clinicians to be aware that EED may predate underlying conditions and the presence of lesions may indicate underlying disease activity. In some cases one may need 'search' for underlying disease. Treatment of these lesions is notoriously difficult. Dapsone is used as the mainstay of treatment, however other options exist. We have highlighted different treatment options and suggested a treatment algorithm. In some cases, treatment may need to be targeted at underlying disease.

show abstract

“…Although its etiology is unclear, it has been shown to be associated with malignancies, infections (HIV and hepatitis), and autoimmune connective tissue diseases. 1 , 2 Multicentric reticulohistiocytosis – Incorrect. This condition is associated with destructive arthropathy, which would have been evident by this point in this patient's lengthy course.…”

Section: Case Reportmentioning

confidence: 99%