Erythema elevtum diutinum and AIDS: art they telated?

Revenga, F; Vera, A; Muñoz, Ángeles Arnandis; Liana, F.G. De La; Alejo, M.; Rodríguez‐Peralto, José Luis

doi:10.1111/j.1365-2230.1997.tb01082.x

Cited by 18 publications

(3 citation statements)

References 5 publications

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“…Extension of the lesions ceased 24 h after initiating CsA. Recently, 2 TEN patients were treated with intravenous CsA (4–5 mg/kg/day) [16, 17]. Within 24 h of starting the drug, the rapid progression of the skin lesions had stopped and by 48 h there was a visible improvement in the erythema after which the skin healed quickly.…”

Section: Csa In Tenmentioning

confidence: 99%

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Would Cyclosporin A Be Beneficial to Mitigate Drug-Induced Toxic Epidermal Necrolysis?

Paquet¹,

Pierard²

1999

Dermatology

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Drug-induced toxic epidermal necrolysis (TEN) is a rare life-threatening disease whose mortality remains high. The treatment of the disease is badly settled. Several kinds of drugs have been tested, including systemic corticosteroids, cyclophosphamide, pentoxifylline and thalidomide, but without any clear-cut outcome. Cyclosporin A (CsA) has many inhibitory effects on the main cell populations involved in TEN (T lymphocytes, macrophages and keratinocytes). CsA could also act on tumor necrosis factor α metabolism, a cytokine which is important in TEN epidermal destruction. Moreover, apoptosis is the mechanism leading to keratinocyte death and CsA has antiapoptotic properties. CsA has already been used successfully on a limited series of TEN patients. We have reviewed the potential theoretical useful effects of CsA in TEN. We conclude that CsA could be a good candidate to reverse TEN progression.

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Section: Csa In Tenmentioning

confidence: 99%

“…Only a very limited number of cases have been treated with other drugs, such as cyclophosphamide [10, 11], pentoxifylline [12], thalidomide [13]and cyclosporin A (CsA) [14, 15, 16, 17]. The present paper reviews the background suggesting that CsA could be a good candidate to abate the evolving TEN process.…”

Section: Introductionmentioning

confidence: 99%

Would Cyclosporin A Be Beneficial to Mitigate Drug-Induced Toxic Epidermal Necrolysis?

Paquet¹,

Pierard²

1999

Dermatology

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“…Most cases reported are idiopathic. However, this rare entity may be associated with a number of systemic diseases such as immunologic disorders, acquired immunodeficiency syndrome, rhematoid arthritis, tuberculosis, malignant tumors, treatment with penicillamine, thyroid disease, renal disorders, Guillain-Barré syndrome, snake bite, and fetal hydrops [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13]. We report herein a case of YNS associated with minimal change nephrotic syndrome.…”

Section: Introductionmentioning

confidence: 99%

Yellow Nails and Minimal Change Nephrotic Syndrome

Yáñez

Val-Bernal²,

Fernández‐Llaca³

1999

Nephron

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We report a case of a 38-year-old man showing the yellow nail syndrome in association with minimal change nephrotic syndrome. Treatment with prednisone and vitamin E resulted in complete resolution of the nephrotic syndrome and slow improvement of the yellow nails, respectively. Although the rare yellow nail syndrome has been described in association with renal disease, this is the first report of the association of this syndrome with minimal change nephrotic syndrome.

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