Erythema gyratum repens‐like eruptions with large cell transformation in a patient with mycosis fungoides

Concentric Annular Truncal Eruption

“…Mycosis fungoides has been reported with an EGR-like eruption in only 8 cases, 3 with a prior history of MF and 5 heralding a new MF diagnosis . Trichophyton rubrum was isolated by culture in 3 patients .…”

“…2,4-9 T-cell receptor gene rearrangement analysis by polymerase chain reaction identified a clone in biopsies from 6 of 8 patients. 2,[4][5][6][7][8] Histopathologic features of EGR were observed in only 1 case. 3 It is unclear whether an EGR-like eruption is associated with a worse prognosis in patients with cutaneous T-cell lymphoma.…”

“…3,4,9 In the remaining patients, there was no evidence for dermatophyte by potassium hydroxide test of scale, periodic acid-Schiff histologic stain, or fungal culture. 2,[5][6][7][8] Underlying lung adenocarcinoma was discovered in 1 case. 2 Skin biopsies of EGRlike eruption associated with MF revealed histopathology consistent with MF alone in all but 1 case.…”

“…1 Mycosis fungoides has been reported with an EGR-like eruption in only 8 cases, 3 with a prior history of MF [3][4][5] and 5 heralding a new MF diagnosis. 2,[6][7][8][9] Trichophyton rubrum was isolated by cul-ture in 3 patients. 3,4,9 In the remaining patients, there was no evidence for dermatophyte by potassium hydroxide test of scale, periodic acid-Schiff histologic stain, or fungal culture.…”

“…9 One patient, besides our patient, had large cell transformation of MF. 7 Two patients experienced MF progression after onset of EGR-like eruption, with 1 developing Sézary syndrome. 4,5 Erythema gyratum repens-like eruption resolved with oral terbinafine treatment in T rubrum-positive cases; however, MF persisted.…”