Erythema multiforme in children

Goldman, Ran D.

doi:10.46747/cfp.6807507

Cited by 16 publications

(11 citation statements)

References 6 publications

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“…Периферический характер действия леводропропизина подтверждается отсутствием влияния на дыхательный центр мозга у пациентов с гиперкапнией и гипоксемией. У этих пациентов препарат не оказывает влияния на содержание двуокиси углерода и кислорода в крови [31,32].…”

Section: возможности использования леводропропизина при остром и подо...unclassified

Role of antitussive agents in the treatment of acute respiratory viral infections and influenza

Fesenko

2023

Medicinskij sovet

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Viral upper respiratory infection (VURI)-associated acute cough is the most common symptom worldwide among children and adults. It causes serious economic and social problems both for individual patients, patients’ families, and the health care system as a whole. There is still no effective pharmacological agent capable of interfering with all the main pathophysiological mechanisms involved in VURI-associated acute cough. This circumstance partly explains the increased prevalence of the prolonged course of acute respiratory infections, when the cough takes on the features of subacute or post-infectious course. The pathophysiology of this symptom is being actively investigated to optimize the treatment of cough. A viral infection provokes an acute cough induced by various irritative stimuli, the main one being secretions from the respiratory tract, which directly acts on reflexogenic areas of the mucosa. Inflammatory mediators also play an important role, acting on the peripheral sensory terminations of airways. Inflammatory mediators also induce post-infectious bronchial hyperreactivity, which is an important component of the pathogenesis of post-infectious cough. Recently, researchers are becoming increasingly interested in the role of the voluntary or conscious cough component, which is implemented due to the cortical response to afferent information from the receptors of the upper respiratory tract.This hypothesis explains the ineffectiveness of central antitussive agents in patients with viral infection-associated dry cough and expands the possibilities of peripheral antitussive agents represented by levodropropizine. In addition to the action on nerve endings, the agent also affects inflammatory mediators, which enhances its ability to break the “vicious circle” of this symptom, prevents the development of post-infectious cough and promotes rehabilitation of the bronchial tree. The efficacy and safety of levodropropizine has been demonstrated in clinical trials in both children and adults.

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Section: возможности использования леводропропизина при остром и подо...unclassified

Role of antitussive agents in the treatment of acute respiratory viral infections and influenza

Fesenko

2023

Medicinskij sovet

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“…Infections are associated with 90% of cases of EM and the most common pathogens in adults are herpes simplex virus (HSV) type 1 and Mycoplasma pneumoniae [ 103 ]. In children infections are once again the most common cause; together with HSV-1 and Mycoplasma Pneumoniae , other pathogens deserve a mention: COVID19, Epstein-Barr virus, cytomegalovirus, vulvovaginal candidiasis [ 104 , 105 ].…”

Section: Other Inflammatory Conditionsmentioning

confidence: 99%

Urticaria: A Narrative Overview of Differential Diagnosis

et al. 2023

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Urticaria is an inflammatory skin disorder that may occur in isolation or associated with angioedema and/or anaphylaxis. Clinically, it is characterized by the presence of smooth, erythematous or blanching, itchy swelling, called wheals or hives, which greatly vary in size and shape and last less than 24 h before fading to leave normal skin. Urticaria is the consequence of mast-cell degranulation that can be caused by immunological or non-immunological mechanisms. From a clinical point of view, many skin conditions can mimic urticaria and their recognition is mandatory for a correct management and therapeutic approach. We have reviewed all of the main relevant studies which addressed differential diagnosis of urticarial, published until December 2022. The National Library of Medicine PubMed database was used for the electronic research. The present review offers a clinical narrative overview, based on the available literature, of the principal skin disorders that can be misdiagnosed as urticaria (mainly autoinflammatory or autoimmune disorders, drug-induced reactions, and hyperproliferative diseases). The aim of this review is to provide clinicians a useful tool for correctly suspecting and identifying all of these conditions.

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“…Bei Auftreten der Gingivostomatitis herpetica sind die Kinder durch Fieber und schmerzhafte Vesikeln und Erosionen perioral stark beeinträchtigt. Deshalb und auch aufgrund der Komplikationen von kutanen bakteriellen Superinfektionen, ZNS-und Augenbeteiligung sollte frühzeitig systemisch mit Aciclovir behandelt werden [25]. Zudem ist auf Flüssigkeitszufuhr sowie symptomatische Mundspülungen und Schmerzbehandlung zu achten.…”

Section: Primärinfektionen: Gingivostomatitis Herpetica (Stomatitis A...unclassified

Kutane Infektionen im Kindesalter

Fölster-Holst

2023

Aktuelle Dermatologie

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ZusammenfassungKutane Infektionen bei Kindern sind häufig, wobei als Auslöser Bakterien, Viren oder Pilze in Betracht kommen. Diese können die epidermalen Zellen direkt von außen oder im Rahmen von systemischen Erkrankungen infizieren, die Hautreaktionen können aber auch durch die Toxinfreisetzung der Bakterien oder als Antwort des Immunsystems auf die Infektionserreger erklärt werden. Beispiele dafür sind das Staphylococcal scalded skin syndrome (SSSS) und Scharlach sowie Exanthemerkrankungen. Darüber hinaus treten sekundäre Infektionen häufig bei Parasitosen auf. Der Artikel fokussiert bakterielle, mykotische und virale Infektionen, wobei bei den letzteren auch Exanthemerkrankungen Erwähnung finden. Aufgrund des umfangreichen Themas, das den Rahmen dieses Heftes sprengen würde, werden nur häufig vorkommende bakterielle, virale und mykotische Hautinfektionen fokussiert und die Exanthemerkrankungen sowie die Parasitosen lediglich tabellarisch dargestellt. Detailliertere Abhandlungen sind entsprechenden angegebenen Referenzen zu entnehmen.

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Erythema multiforme in children

Cited by 16 publications

References 6 publications

Role of antitussive agents in the treatment of acute respiratory viral infections and influenza

Role of antitussive agents in the treatment of acute respiratory viral infections and influenza

Urticaria: A Narrative Overview of Differential Diagnosis

Kutane Infektionen im Kindesalter

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