Rook's Textbook of Dermatology 2010
DOI: 10.1002/9781444317633.ch76
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Erythema Multiforme, Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis

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Cited by 22 publications
(24 citation statements)
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“…[5] Females appear to have a greater predilection for developing toxic epidermal necrolysis than males. [6] Though the main culprit drugs include sulfonamides, antiepileptic drugs, ampicillin, allopurinol and NSAIDs, toxic epidermal necrolysis is rarely reported with ciproß oxacin. [6] Agranulocytosis is another rare life threatening complication of ciprofloxacin.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…[5] Females appear to have a greater predilection for developing toxic epidermal necrolysis than males. [6] Though the main culprit drugs include sulfonamides, antiepileptic drugs, ampicillin, allopurinol and NSAIDs, toxic epidermal necrolysis is rarely reported with ciproß oxacin. [6] Agranulocytosis is another rare life threatening complication of ciprofloxacin.…”
Section: Discussionmentioning
confidence: 99%
“…[6] Though the main culprit drugs include sulfonamides, antiepileptic drugs, ampicillin, allopurinol and NSAIDs, toxic epidermal necrolysis is rarely reported with ciproß oxacin. [6] Agranulocytosis is another rare life threatening complication of ciprofloxacin. [3] The overall incidence of non chemotherapy drug induced agranulocytosis ranges from 2.6 to 10 cases per million patients exposed to drugs per year.…”
Section: Discussionmentioning
confidence: 99%
“…SJS/TEN are of major concern because of severe morbidity and high mortality rates reported from less than 10% in SJS patients to more than 40% in TEN patients (overall 20-25%) (Valeyrie-Allanore and Roujeau, 2008;Breathnach, 2010). Because of the rareness of the reaction (Europe: 1.5-2 patients/year/million people), knowledge is often derived from case reports or small cohorts, leaving several questions unanswered (Naldi et al, 1990;Roujeau et al, 1990;Rzany et al, 1996).…”
Section: Introductionmentioning
confidence: 98%
“…Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe cutaneous adverse reactions (SCAR) mainly induced by drugs (Valeyrie-Allanore and Roujeau, 2008;Mockenhaupt, 2009;Breathnach, 2010).…”
Section: Introductionmentioning
confidence: 99%
“…4 Clinically it presents as macular, papular or urticarial lesions as well as the classical "target lesions" distributed preferentially on the distal extremities. 5 Cases of Herpes associated erythema multiforme (HAEM) can often be confused with Steven-Johnsons syndrome (SJS) and Toxic epidermal necrolysis (TEN). HAEM can be distinguished from SJS by the presence of typical target lesions on the skin with or without mucosal involvement.…”
Section: Introductionmentioning
confidence: 99%