Erythema Multiformlike Reaction Caused by Topical Application of Thuja Essential Oil

Puig, Lluís; Alomar, A.; Randazzo, L; Cuatrecasas, Míriam

doi:10.1097/01634989-199406000-00008

Cited by 7 publications

(1 citation statement)

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“…In our patient typical target lesions with a central vesicular element were seen, the rash was more pronounced on the arm of the tattoo, sparing the immediate vicinity, and involved the acral areas. The histology is variable; typical features of EM may be seen (16), but nonspecific features, as in our patient, with a spongiotic dermatitis with perivascular lymphocytic and eosinophilic infiltrates, can be seen (13,17).…”

Section: Discussionmentioning

confidence: 67%

Vesicular Erythema Multiforme‐like Reaction to Para‐Phenylenediamine in a Henna Tattoo

Sidwell

Francis

Basarab

et al. 2008

Pediatric Dermatology

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Allergic contact dermatitis reaction to topical ''black henna'' tattoo is usually described secondary to the organic dye para-phenylenediamine, a derivative of analine. Allergic contact dermatitis reactions to paraphenylenediamine are well recognized and most commonly involve an eczematous reaction that may become generalized and an acute angioedema. Only four previous instances have been reported of an erythema multiforme-like reaction to para-phenylenediamine and its derivatives, including only one mild reaction to a tattoo. A vesicular erythema multiformelike reaction has not been reported. An erythema multiforme-like reaction to contact allergens is usually caused by potent allergens including plant quinolones in Compositae and sesquiterpene lactones in exotic woods, and it is also reported to topical drugs, epoxy resin, metals (particularly nickel), and various chemicals. A generalized vesicular erythema multiforme-like reaction is unusual, and rarely reported. We describe a 6-year-old boy who developed a localized, eczematous and severe generalized vesicular erythema multiforme-like contact allergy to para-phenylenediamine secondary to a henna tattoo. As henna tattoos are becoming increasingly popular, one should be aware of the possibility of such a reaction. This presentation also highlights the call to ban the use of para-phenylenediamine and its derivatives in dyes.

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Section: Discussionmentioning

confidence: 67%