“…In the past, the prognosis was based mainly on serum antibody titres (Kelsall and Vos, 1952;Tovey and Valaes, 1959;Dique and Wrench, 1959;MacKay, 1961), but recently estimation of the bilirubin content of amniotic fluid has been considered a more accurate method of prediction. In the past, the prognosis was based mainly on serum antibody titres (Kelsall and Vos, 1952;Tovey and Valaes, 1959;Dique and Wrench, 1959;MacKay, 1961), but recently estimation of the bilirubin content of amniotic fluid has been considered a more accurate method of prediction.…”