Erythroderma due to ribostamycin

Abstract

A 48-year-old man became erythrodermatous after intramuscular administration of ribostamycin, an aminoglycoside antibiotic in the same family as neomycin. Patch tests were positive to ribostamycin and neomycin, as well as to mercurials. There was no mercurial preservative in the injection solution. A lymphocyte transformation test was positive for ribostamycin and tobramycin, but not for gentamycin. Diagnostic and structure-activity relationship aspects of the case are discussed.

Anaphylaxis due to ribostamycin

“…Ribostamycin is an aminoglycoside antibiotic in the same family as neomycin. Erythroderma was proven after intramuscular administration of ribostamycin (3). No report of anaphylaxis because of ribostamycin has been published.…”