¿Es necesaria la orquidectomía en los pacientes con testículo no descendido post-puberal?

Loarca, E.A. Granados; Ortega, Silvana

doi:10.1016/s0210-4806(05)73378-7

Cited by 5 publications

(2 citation statements)

References 16 publications

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“…One of the testes was found to have a malignancy consisting of a pure seminoma. In the subsequent follow-up period, none of the patients in either group (orchiopexy or orchiectomy) developed a malignancy in the contralateral testis [ 23 ].…”

Section: Treatment Of Postpubertal Cryptorchidismmentioning

confidence: 99%

Individualized Treatment Guidelines for Postpubertal Cryptorchidism

Chung

2015

World J Mens Health

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Cryptorchidism is a well-known congenital anomaly in children. However, its diagnosis is often delayed for reasons including patient unawareness or denial of abnormal findings in the testis. Moreover, it has been difficult to establish an optimal treatment strategy for postpubertal cryptorchidism, given the small number of patients. Unlike cryptorchidism in children, postpubertal cryptorchidism is associated with an increased probability of neoplasms, which has led orchiectomy to be the recommended treatment. However, routine orchiectomy should be avoided in some cases due to quality-of-life issues and the potential risk of perioperative mortality. Based on a literature review, this study proposes individualized treatment guidelines for postpubertal cryptorchidism.

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Section: Treatment Of Postpubertal Cryptorchidismmentioning

confidence: 99%

Individualized Treatment Guidelines for Postpubertal Cryptorchidism

Chung

2015

World J Mens Health

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“…Furthermore, 5% of all testicular cancers are associated with cryptorchidism. Granados Loarca and Esau Ortega [ 8 ] reported that one of the 25 (4%) postpubertal undescended testis patients they assessed had seminoma, and similarly, Ben Jeddou et al [ 9 ] found that two of 81 patients aged >14 years with undescended testis had malignant disease. In the present study, one of the 34 men with untreated postpubertal undescended testis was diagnosed as having ITGCN.…”

Section: Discussionmentioning

confidence: 99%

The incidence and histological characteristics of intratubular germ cell neoplasia in postpubertal cryptorchid testis

et al. 2015

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PurposeIt is well known that testicular germ cell tumors arise with increased frequency in patients with cryptorchidism. In addition, intratubular germ cell neoplasia (ITGCN) is a precursor lesion to testicular germ cell tumor. Approximately 50% of patients with ITGCN will develop an invasive of testicular germ cell tumors within 5 years. Therefore, we evaluated that the incidence of ITGCN in postpubertal cryptorchidism.Materials and MethodsBetween January 2002 and August 2012, orchiectomy specimens from 31 postpubertalpatients (aged 12 or over) with cryptorchid testis were reviewed. The specimens were evaluated for ITGCN using immunohistochemical stains of placental-like alkaline phosphatase and Oct 3/4 with routine hematoxylin-eosin stain. Additionally, the degree of spermatogenesis was assessed using the Johnsen score.ResultsMean age was 34 years (range, 17 to 74 years) at surgery. All patients were diagnosed as unilateral cryptorchidism. One patient (3.2%) of 20-year-old had ITGCN in surgical specimen with all positive markers. Histological assessment of spermatogenesis showed that mean Johnsen score was 3.42 (range, 1 to 9). Majority of patients (27 of 31) presented impaired spermatogenesis with low Johnsen score lesser than 5.ConclusionsConsidering the risk of malignancy and low spermatogenesis, we should perform immunohistochemical stains and discuss preventative orchiectomy for the postpubertal cryptorchidism.

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Résection laparoscopique pour carcinome hépatocellulaire périphérique sur hépatopathie chronique

Dousset

Mestier

Vons

2006

Journal de Chirurgie

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¿Es necesaria la orquidectomía en los pacientes con testículo no descendido post-puberal?

Abstract: In the following up of the patients none of them presented contralateral testicle cancer between 5-10 years. The patients who were practiced the orchiopexy no-one presented testicular cancer between 5-11 years.

Cited by 5 publications

References 16 publications

Individualized Treatment Guidelines for Postpubertal Cryptorchidism

Individualized Treatment Guidelines for Postpubertal Cryptorchidism

The incidence and histological characteristics of intratubular germ cell neoplasia in postpubertal cryptorchid testis

Résection laparoscopique pour carcinome hépatocellulaire périphérique sur hépatopathie chronique

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