Escherichia coli Infection in Piglets

Pathogenicity of an Enterotoxigenic Escherichia coli Hemolysin ( hlyA ) Mutant in Gnotobiotic Piglets

“…The finding of ETEC within cytoplasmic vacuoles of columnar enterocytes may reflect the predisposition of neonatal gnotobiotic piglet intestine to phagocytose bacteria and/or an invasive capacity of the serotype used for inoculation (16,19,25,30,35). ETEC is not considered to be invasive in the classical sense (26).…”

The effect of the use of antibacterial drugs, particularly as food additives, on the emergence of drug-resistant strains of bacteria in animals

“…Glantz (1962), too, found a high incidence of tetracycline resistance, 100 of 158 strains, amongst pathogenic strains of E. coli isolated from diseased pigs in that country. Apart from this undesirable effect of tetracyclines employed nutritionally, it is becoming increasingly apparent that the frequent prophylactic or therapeutic use in a pig herd of any of the available anti-bacterial drugs eventually results in the particular drug becoming largely ineffective in the treatment of E. coli infections in that herd, and other drugs have to be used (Saunders et al, 1960;Aynsley, 1961;Davies, 1961;Smith and Jones, 1961). The inevitable outcome of the present policy of drug administration in pig herds as far as the therapy of E. coli infections is concerned is illustrated by the recent studies of Smi th (1966).…”

Escherichia coli and Neonatal Disease of Calves

“…There is not as much in the literature regarding serotypes isolated from piglet colibacillosis; however, it is apparent that some of the serotypes associated with gut edema and coliform gastroenteritis are involved to some extent, because the serotypes 08:K87(B? )K88L:H19, 0138:K-81 (B), 0139:K82(B), 0141 :K85ab(B)K88(L) :H4, and also 0133:K88(L):Hl9 have been isolated from septicemia, or enteritis, or both in piglets (126,174,182,219). However, this emphasis on the importance of these serotypes may be somewhat biased, because, apart from the study of Saunders et al (182), these studies dealt purely VOL.…”

“…)K88L:H19, 0138:K-81 (B), 0139:K82(B), 0141 :K85ab(B)K88(L) :H4, and also 0133:K88(L):Hl9 have been isolated from septicemia, or enteritis, or both in piglets (126,174,182,219). However, this emphasis on the importance of these serotypes may be somewhat biased, because, apart from the study of Saunders et al (182), these studies dealt purely VOL. 29,1965 on July 6, 2020 by guest http://mmbr.asm.org/ Downloaded from with hemolytic E. coli and, hence, might tend to exaggerate the importance of these serotypes.…”