Esclerose lateral amiotrófica esporádica: critérios diagnósticos

Godoy, J. M.; Oliveira, Marcelo A. R. de; Neto, João B. Mascarenhas de Moraes; Balassiano, S. L.; Montagna, Nádia; Pinto, José Roberto Aparecido dos Santos; Skacel, M.

doi:10.1590/s0004-282x1993000200015

Cited by 4 publications

(1 citation statement)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similarly, hypophosphatemia and calcium disorders secondary to hyperparathyroidism can sometimes cause the same. 43 With regard to pharmacological treatments, in a pioneering experimental study Wigiton and Masland concluded that neostigmine may cause fasciculations potentials by increasing the concentration of acetylcholine in the neuromuscular junction in felines. 6 Discharges are caused by the direct effect of acetylcholine on motor nerve terminals.…”

Section: Fasciculations Induced By Systemic Diseases Drugs And/or Inmentioning

confidence: 99%

Another perspective on fasciculations: when is it not caused by the classic form of amyotrophic lateral sclerosis or progressive spinal atrophy?

Leite¹,

Orsini²,

Freitas³

et al. 2014

Neurol Int

View full text Add to dashboard Cite

Fasciculations are visible, fine and fast, sometimes vermicular contractions of fine muscle fibers that occur spontaneously and intermittently. The aim of this article is to discuss the main causes for fasciculations and their pathophysiology in different sites of the central/peripheral injury and in particular to disprove that the presence of this finding in the neurological examination is indicative of amyotrophic lateral sclerosis. Undoubtedly, most fasciculations have a distal origin in the motor nerve both in normal subjects and in patients with motor neuron disease. Most of them spread to other dendritic spines often producing an antidromic impulse in the main axon. The clinical and neurophysiological diagnosis must be thorough. It may often take long to record fasciculations with electroneuromyography. In other cases, temporal monitoring is necessary before the diagnosis. The treatment, which may be adequate in some cases, is not always necessary.

show abstract

Section: Fasciculations Induced By Systemic Diseases Drugs And/or Inmentioning

confidence: 99%