“…Sclerotherapy is an effective, conservative and safe technique for the treatment of OV, and monoethanolamine oleate has been widely used in their management 8,46 . Others sclerosing agents used are 5% sodium morrhuate, sodium psylliate, quinine urethrone, 1% polidocanol, sodium tetradecyl sulphate, ethanol 51 and hypertonic saline 23,46,52 . The mechanism of action is based on the damage of the endothelium, causing a protein denaturalisation, which induces endothelial damage, thrombus formation, sclerosis, immediate vascular occlusion, consequent inflammation and the subsequent associated fibrosis 51,53 .…”