Esculentoside S : A New Saponin from the Leaves ofPhytolacca acinosa

Abstract

From the leaves of Phytolacca acinosa a new glycoside, named esculentoside S has been identified as 3-0-~-D-xylopyranosyl-28-0-~-D-glucopyranosyl-phytolaccagenin. Besides this the known 2 glycosides esculentoside A and esculentoside B were found.

Bioactive Triterpene Saponins from the Roots of Phytolacca americana

“…The δ C values of compounds 3 were in good agreement with those of 7 including the resonances around the glycosyl bonds at C-3 and C-28 and sugar moieties (Table S6), except those of the carbons that were influenced by the methoxy group at C-11 of 3 . In addition, [α] D values of 3 (+62.6) and 7 (+45.0) had the same sign. Thus, the full structure of phytolaccasaponin N-3 ( 3 ) was proposed as 3- O -[β- d -glucopyranosyl-(1→4)]-β- d -xylopyranosyl]-11α-methoxyphytolaccagenin.…”

“…Since only d -glucose and d -xylose are known in P . esculenta ,,– , and P. americana , ,,– the sugar portions in 1 were assigned as 3- O -[β- d -glucopyranosyl-(1→4)-β- d -xylopyranoside] and 28- O -(β- d -glucopyranoside). In the course of isolation of 1 , esclentoside H ( 6 ) was isolated as the most abundant product.…”

“…Since only d -glucose and d -xylose are known in P . esculenta ,,– , and P. americana , ,,– the glycosyl moiety at the C-3 position was deduced to be 3- O -β- d -glucopyranosyl-(1→2)-[β- d -glucopyranosyl-(1→4)]-β- d -xylopyranoside. Therefore, compound 5 was assigned as 28- O -(β- d -glucopyranosyl)-3- O -{β- d -glucopyranosyl-(1→2)[β- d -glucopyranosyl-(1→4)]-β- d -xylopyranosyl}phytolaccagenic acid ( 5 ).…”

“…Both plants were introduced to Japan from their native countries, with P. americana now found there in both grasslands and open forests. The constituents of P. esculenta – ,– , and P. americana ,,,– have been investigated by many researchers with an interest in their biological activities. We have conducted a further investigation on the roots of P. americana and describe the saponins obtained and their biological activities.…”

Triterpene Saponins from the Fruits of Phytolacca rugosa (Phytolaccaceae)

“…The compounds isolated from P. rugosa fruits (1-4) were unambiguously identified by 2D NMR spectroscopy and mass spectrometry (FAB) as: Chemotaxonomic significance: Of the 41 genera of the Phytolaccaceae family, Phytolacca, comprising above 70 species, is widespread in tropical and temperate regions [12]. In this genus, saponins with a triterpenic aglycon, such as serjanic acid, have been isolated from P. icosandra [7], P. rivinoides [11], P. bogotensis [11], P. tetramera [13], P. americana [9], P. polyandra [14], P. acinosa [15], P. dodecandra [16], P. esculenta [17], P. thyrsiflora [10], P. octandra [18], P. insularis [19], and P. abyssinica [20]. For the first time the known compounds 1-4 were found in P. rugosa, which is in accordance with the chemotaxonomy of the Phytolacca genus.…”