2019
DOI: 10.22159/ajpcr.2020.v13i2.35511
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Eslicarbazepine and Memory Impairment in Temporal Lobe Epilepsy: A Study on the Attenuating Effect of Nefiracetam

Abstract: Objectives: The objectives of the present investigation were to evaluate the memory impairment (MI) activity of eslicarbazepine (ESL) in temporal lobe epilepsy (TLE) at a normal and reduced dose, to evaluate the possible protective effect of nefiracetam (NEF) on MI induced by ESL at a normal and reduced dose, and to evaluate the antiepileptic activity of ESL on TLE in the presence and absence of NEF. Methods: MI activity was evaluated by Barnes maze (BM) on lithium-pilocarpine-induced TLE in Wistar albin… Show more

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