Esophageal Eosinophilic Disease After Intestinal Transplantation in Children

Khan, Khalid; Desai, Chirag S.; Fishbein, Thomas M.; Kaufman, Stuart S.

doi:10.1097/tp.0000000000000278

Cited by 3 publications

(4 citation statements)

References 9 publications

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“…42 Khan et al reported a prevalence of EoE of 32% in children who underwent transplantion between 2003 and 2012, with cow's milk protein and egg being the most common allergens. 43 Arnold et al reported a higher prevalence of EoE (58%) in children who received an intestinal or multivisceral transplant during the same period (2003-2016). 44 In addition, those with EoE had a higher frequency of rejection episodes and prior diagnosis of posttransplant lymphoproliferative disorder.…”

Section: Macronutrient Considerationsmentioning

confidence: 99%

“…Dairy products, wheat, egg, and soy have been identified as common triggers for EoE in the general population, with symptoms including decreased appetite, abdominal pain, difficulty swallowing, or vomiting 42 . Khan et al reported a prevalence of EoE of 32% in children who underwent transplantion between 2003 and 2012, with cow's milk protein and egg being the most common allergens 43 . Arnold et al reported a higher prevalence of EoE (58%) in children who received an intestinal or multivisceral transplant during the same period (2003–2016) 44 .…”

Section: Macronutrient Considerationsmentioning

confidence: 99%

See 1 more Smart Citation

Nutrition support considerations in pediatric small bowel transplantation

Nucci,

Crim,

King

et al. 2023

Nut in Clin Prac

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Enteral autonomy is the primary goal of intestinal failure therapy. Intestinal transplantation (ITx) is an option when enteral autonomy cannot be achieved and management complications become life‐threatening. The purpose of this review is to summarize existing medical literature related to nutrition requirements, nutrition status, and nutrition support after pediatric ITx. Achieving or maintaining adequate growth after intestinal transplant in children can be challenging because of episodes of rejection that require the use of corticosteroids, occurrences of infection that require a reduction or discontinuation of enteral or parenteral support, and fat malabsorption caused by impaired lymphatic circulation. Nutrient requirements should be assessed and modified regularly based on nutrition status, growth, ventilatory status, wound healing, and the presence of complications. Parenteral nutrition (PN) should be initiated as a continuous infusion early postoperatively. Enteral support should be initiated after evidence of graft bowel function and in the absence of clinical complications. Foods high in simple carbohydrates should be limited, as consumption may result in osmotic diarrhea. Short‐term use of a fat‐free diet followed by a low‐fat diet may reduce the risk of the development of chylous ascites. Micronutrient deficiencies and food allergies are common occurrences after pediatric ITx. Enteral/oral vitamin and mineral supplementation may be required after PN is weaned. Nutrition management of children after ITx can be challenging for all members of the healthcare team. Anthropometric parameters and micronutrient status should be monitored regularly so that interventions to promote growth and prevent or reverse nutrient deficiencies can be implemented promptly.

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Section: Macronutrient Considerationsmentioning

confidence: 99%

Section: Macronutrient Considerationsmentioning

confidence: 99%

Nutrition support considerations in pediatric small bowel transplantation

Nucci,

Crim,

King

et al. 2023

Nut in Clin Prac

View full text Add to dashboard Cite

show abstract

“…It has also been reported in pediatric patients that food allergy may be increased after solid organ transplantation. While there are reports in other organ solid organ transplant groups the greatest number of publications has been from liver transplant populations with the implication that immune dysregulation with tendency towards a T-helper cell 2 response may be the mechanism [5] . We have recently described an increase in prevalence of food allergy in children after ITx similar to liver pediatric liver transplant patients [5] .…”

Section: Transplant Outcomesmentioning

confidence: 99%

“…While there are reports in other organ solid organ transplant groups the greatest number of publications has been from liver transplant populations with the implication that immune dysregulation with tendency towards a T-helper cell 2 response may be the mechanism [5] . We have recently described an increase in prevalence of food allergy in children after ITx similar to liver pediatric liver transplant patients [5] . We postulate that immune dysregulation in the liver in addition to abnormal uptake of food proteins by the transplanted intestine may be cumulative in development of food allergy in patients after ITx.…”

Section: Transplant Outcomesmentioning

confidence: 99%

Trends in Intestinal Transplantation

Habib¹

2015

JAS

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The role of endoscopy in the small intestinal transplant recipient: A review

Crismale

Mahmoud

Moon

et al. 2021

American Journal of Transplantation

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Intestinal transplantation (ITx) is the treatment of choice for patients with intestinal failure (IF) who have developed complications related to total parenteral nutrition (TPN), including recurrent line sepsis, intestinal failure-associated liver disease, and complications related to vascular access. 1 Approximately 40% of patients on the ITx waiting list require ITx as part of combined liver-intestine transplantation or multivisceral transplantation (MVTx), with indications including primary end-stage liver disease complicated by porto-mesenteric thrombosis or secondary liver failure related to long-term TPN use. 2

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Esophageal Eosinophilic Disease After Intestinal Transplantation in Children

Cited by 3 publications

References 9 publications

Nutrition support considerations in pediatric small bowel transplantation

Nutrition support considerations in pediatric small bowel transplantation

Trends in Intestinal Transplantation

The role of endoscopy in the small intestinal transplant recipient: A review

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