“…Because of the large tumor size and unclear boundaries with surrounding tissues, all previously reported giant leiomyomas of the esophagus [2,3,5-10] were treated by open thoracotomy or tumor resection through a thoracoabdominal incision in combination with gastroesophagostomy. Traditional open thoracotomy can cause relatively serious operative trauma and negatively affects postoperative respiratory function and diet restoration, in addition to inevitable anastomotic complications [3,6,11], all of which can worsen the prognosis. In recent years, a series of domestic and international centers have gradually implemented minimally invasive surgeries for the treatment of esophageal leiomyoma, including resection or enucleation [12-18] of esophageal leiomyoma by thoracoscopy [1,4,11], laparoscopy [1,4], or Da Vinci robot-assisted thoracoscopy [19].…”