Esophageal squamous cell carcinoma in children: A case presentation and review of an unusual entity

Süslü, Nilda; Senirli, Rezarta Taga; Hoşal, Ali Şefik; Mocan, Burçe Özgen; Cengiz, Mustafa

doi:10.1016/j.pedex.2011.12.002

Cited by 1 publication

(1 citation statement)

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“…Dawsey et al 27 found 145 cases ≤30 years of age in the literature published between 1925 and 2007. We could find only 40 cases of esophageal carcinoma diagnosed under 18 years of age in the literature 5–24,28–37 (Table 2). This included 29 males and 11 females, with a M/F ratio of 2.6/1.…”

Section: Discussionmentioning

confidence: 99%

Esophageal Carcinoma in Children: Report of 2 Cases and a Review of the Literature

Coşkun,

Kurucu,

Kutluk

et al. 2023

Journal of Pediatric Hematology/Oncology

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Esophageal carcinoma in children and adolescents is extremely rare. Here, we report 2 cases of pediatric esophageal carcinoma presenting with progressive dysphagia. There was not any underlying specific risk factor in our cases. The histopathological subtypes were adenocarcinoma in one and squamous cell carcinoma in another case. Response to combined modality treatment was good in the case of adenocarcinoma, while the patient with squamous cell carcinoma was unresponsive to treatment and died of the progressive disease. We reviewed the pediatric cases of esophageal carcinoma reported in the literature. Progressive dysphagia was observed in 89% of these cases. One third of pediatric cases had underlying risk factors. Squamous cell carcinoma is a more common type of childhood esophageal carcinoma. In contrast to adults, pediatric esophageal squamous cell carcinoma may distribute throughout the esophagus. Esophageal adenocarcinoma was seen in the distal esophagus in pediatric cases. Metastatic disease was found in 48% of pediatric patients at presentation, and the prognosis is poor. Collaborative efforts are needed for success in the treatment of esophageal carcinoma.

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Section: Discussionmentioning

confidence: 99%