Esophageal tuberculosis

Rosario, Manuel T.; Raso, Carl L.; Comer, Gail M.

doi:10.1007/bf01537279

Cited by 40 publications

(17 citation statements)

References 13 publications

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“…The esophagus at the tracheal bifurcation is commonly involved, because the most frequent mechanism of esophageal tuberculosis is the direct extension of tuberculous lymphadenitis from the hilar and/or mediastinal lymph nodes. 1,[7][8][9] uninformative, a therapeutic trial was started, with great care for the possibility of malignancy. We used isoniazid, rifampicin, and ethambutol.…”

Section: Discussionmentioning

confidence: 99%

Esophageal tuberculosis presenting with an appearance similar to that of carcinoma of the esophagus

Fujiwara

Osugi

Takada

et al. 2003

Journal of Gastroenterology

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A case of esophageal tuberculosis presenting with an appearance similar to that of esophageal cancer is reported. The patient was an 82-year-old man with progressive dysphagia. Barium swallow and esophagoscopy revealed an elevated lesion with deep ulceration in the middle thoracic esophagus. Esophageal carcinoma, in particular, an undermining type of undifferentiated carcinoma, was suspected fluoroscopically and endoscopically. Histological examination of biopsy specimens revealed no malignancy, but there were epithelioid granulomas and a few Langhans' type multinucleated giant cells. Endoscopic ultrasonography clearly demonstrated an extramural lesion with calcification and direct infiltration of enlarged subcarinal lymph nodes into the esophageal wall. Ultrasonographic and histological findings indicated the possibility of esophageal tuberculosis. Although no bacteriological evidence was obtained, a therapeutic trial for tuberculosis, using antituberculous drugs, was started. After 2 weeks, the enlarged subcarinal lymph nodes were markedly reduced in size. The patient's symptoms improved gradually and had disappeared 8 weeks after he started treatment, when tubercle bacilli were isolated from sputum. A connection between the esophageal wall and its adjacent structures was clearly demonstrated by endoscopic ultrasonography. For patients with findings indicative of esophageal tuberculosis on endoscopic ultrasonography, a therapeutic trial for tuberculosis should be considered, even if polymerase chain reaction assay or culture is negative.

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Section: Discussionmentioning

confidence: 99%

Esophageal tuberculosis presenting with an appearance similar to that of carcinoma of the esophagus

Fujiwara

Osugi

Takada

et al. 2003

Journal of Gastroenterology

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“…Fluctuation of enlarged lymph nodes and discharging sinuses during treatment have also been documented.4 Oesophageal tuberculosis, however, usually results from direct extension of caseating subcarinal lymph nodes. 6 The stratified squamous epithelium and the short transit time through it render the normal oesophagus resistant to invasion by swallowed tubercle bacilli.67 Two striking observations in this patient, however, need to be highlighted. Firstly, the severity of the reaction to tuberculoprotein which led to ulceration of the mucosal surface of the otherwise relatively spared oesophagus4 eight weeks after starting treatment and, secondly, the progression of the reaction in the mediastinal nodes in the face of resolution of the cervical lymphadenopathy.…”

Section: Discussionmentioning

confidence: 89%

Oesophageal tuberculosis mimicking a tumour during treatment for nodal tuberculosis.

Kaur

Katariya²,

Bhusnurmath³

et al. 1993

Thorax

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A patient with cervical lymph node tuberculosis developed a tubercular ulcer in the oesophagus eight weeks after starting treatment. This was probably due to a drug related hypersensitivity reaction in an adjacent mediastinal lymph node and subsided with continued treatment. (Thorax 1993;48:772-773) Despite the frequent involvement of other mediastinal structures,' oesophageal tuberculosis is rare. We describe a patient with tuberculous ulceration of the oesophagus mimicking a mass lesion which appeared eight weeks after institution of antituberculous treatment.Case report A 26 year old housewife presented with general ill health and fatigue for 2-3 months. She

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“…Patients can present with stricture, pseudotumours, mucosal ulcers or fistulae or a sinus tract ulcerating into mediastinum [6]. Mediastinal lymph node involvement secondary to tuberculosis can cause pressure changes, adhesions or involve the esophagus, which may be picked up on imaging.…”

Section: Discussionmentioning

confidence: 98%