Esophageal varices and their treatment by injection

Tolan, John F.

doi:10.1288/00005537-194904000-00012

Cited by 9 publications

(1 citation statement)

References 6 publications

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“…Yet, a recurrence rate of 14.7% to 60% (1-4) and a rebleeding rate of 13.2% to 55.3% (2, 5-10) with sclerotherapy have been reported, not differing much from the early reports on sclerotherapy, in spite of significant recent improvement in instruments and materials (22,23). At the inception of sclerotherapy, splenectomy had been tried during or after the treatment for esophageal varices to reduce the recurrence rate (24,25). MacBeth had evaluated a combined ther- apy of splenectomy and sclerotherapy for esophageal varices because the splenectomy blocked the variceal blood supply route and, at the same time, caused a significant decrease in portal blood flow (25).…”

Section: Discussionmentioning

confidence: 99%

Recurrence Factors Studied by Percutaneous Transpepatic Portography Before and After Endoscopic Sclerotherapy for Esophageal Varies

et al. 1990

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High recurrence and rebleeding rates have been reported when endoscopic sclerotherapy has been performed on patients with esophageal varices. We studied the relationship between embolization range and recurrence rate in 26 patients in whom percutaneous transhepatic portography was carried out before and after sclerotherapy. Patients were divided into complete and incomplete embolization groups. The complete embolization group consisted of 16 patients whose esophageal varices had disappeared and in whom embolization of the feeders to the varices had occurred. The incomplete embolization group consisted of 10 patients whose esophageal varices had disappeared, but no embolization had occurred. Recurrence rates within 2 yr after the treatment were compared between complete and incomplete embolization groups. The recurrence rates in the respective groups were 6.7% (1 of 15) and 70.0% (7 of 10), indicating a significant difference between the two groups (p less than 0.05) and indicating that embolization of both esophageal varices and their feeders is essential to lower the recurrence rate after sclerotherapy.

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