Esophagitis and anticonvulsant hypersensitivity syndrome

Balatsinou, Chrysanthi; Milano, Angelo; Laterza, Francesco; Mp, Caldarella; Angelucci, Domenico; Vecchiet, Jacopo; Zingariello, Pompea; Falasca, Katia; Lapenna, Domenico; Neri, Matteo

doi:10.1055/s-2006-925130

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Aero-allergens and food allergens have been implicated [8], as well as two cases observed in carbamazepine-induced hypereosinophilic syndrome [9]. Interestingly, carbamazepine is the most commonly implicated medication in DRESSs syndrome.…”

Section: Discussionmentioning

confidence: 99%

“…Eosinophilic oesophagitis has become a well-described phenomenon and is felt to represent an allergic response to an allergen, mediated by T helper 2 cells, IL-5, and IgE [ 7 ]. Aero-allergens and food allergens have been implicated [ 8 ], as well as two cases observed in carbamazepine-induced hypereosinophilic syndrome [ 9 ]. Interestingly, carbamazepine is the most commonly implicated medication in DRESSs syndrome.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

An Unusual Cause of Anaemia of Chronic Disease: Lisinopril-Induced Chronic Inflammatory State

Eyre

Van-Hamel-Parsons

Wang

et al. 2011

Case Reports in Hematology

View full text Add to dashboard Cite

We report the case of a patient with severe systemic symptoms (weight loss, malaise, and anorexia), eosinophilic oesophagitis, and raised inflammatory markers coinciding with the use of lisinopril. The onset of symptoms occurred after the administration of lisinopril and resolved shortly after cessation of the medication. Despite thorough investigation, no other cause of the systemic inflammation and anaemia of chronic disease was found. “Drug rash with eosinophilia and systemic symptoms” (DRESSs) syndrome describes a potentially serious multiorgan inflammatory response to certain classes of drugs; this includes the use of ACE inhibitors. Although this patient did not meet strict criteria for DRESSs, the subacute inflammatory syndrome with eosinophilic organ infiltration bears similar features. ACE inhibitors should be considered in the differential diagnosis in patients with nonspecific systemic inflammation and anaemia of chronic disease where no other cause is found.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

An Unusual Cause of Anaemia of Chronic Disease: Lisinopril-Induced Chronic Inflammatory State

Eyre

Van-Hamel-Parsons

Wang

et al. 2011

Case Reports in Hematology

View full text Add to dashboard Cite

show abstract

Eosinophilic esophagitis is a component of the anticonvulsant hypersensitivity syndrome: Description of two cases

Balatsinou

Milano

Caldarella

et al. 2008

Digestive and Liver Disease

View full text Add to dashboard Cite

Eosinophilic esophagitis

Gupte¹,

Draganov²

2009

WJG

View full text Add to dashboard Cite

Eosinophilic esophagitis is increasingly recognized in adults. The diagnosis is based on the presence of both typical symptoms and pathologic findings on esophageal biopsy. Patients usually present with dysphagia, food impaction and/or reflux-like symptoms, and biopsy of the esophagus shows more than 15 eosinophils per high-power field. In addition, it is essential to exclude the presence of known causes of tissue eosinophilia such as gastroesophageal reflux disease, infections, malignancy, collagen vascular diseases, hypersensitivity, and inflammatory bowel disease. There are no standardized protocols for the therapy of eosinophilic esophagitis. A variety of therapeutic approaches including acid suppression, dietary modifications, topical corticosteroids and endoscopic dilation can be used alone or in combination.

show abstract

Esophagitis and anticonvulsant hypersensitivity syndrome

Cited by 3 publications

References 0 publications

An Unusual Cause of Anaemia of Chronic Disease: Lisinopril-Induced Chronic Inflammatory State

An Unusual Cause of Anaemia of Chronic Disease: Lisinopril-Induced Chronic Inflammatory State

Eosinophilic esophagitis is a component of the anticonvulsant hypersensitivity syndrome: Description of two cases

Eosinophilic esophagitis

Contact Info

Product

Resources

About