ESR rate can be a marker for coronary artery disease

Eftekhaari, Tasnim Eghbal

doi:10.2147/vhrm.s39006

Cited by 6 publications

(3 citation statements)

References 7 publications

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“…ESR values increased by 4.7 mm/h (P = 0.03), and US-CRP levels increased by 1.6 mg/mL (P < 0.01). Several clinical studies have associated elevated ESR levels with an increased risk of mortality from coronary artery disease and the progression of atherosclerosis [ 31 - 32 ]. Erikssen et al [ 33 ] assessed ESR in healthy patients aged 40 to 60 years, and the test was repeated after a 7-year follow-up.…”

Section: Discussionmentioning

confidence: 99%

Progression of subclinical cardiovascular disease in patients with HIV

Fayos,

Arnaiz de las Revillas,

González Quintanilla

et al. 2024

Rev Esp Quimioter

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Introduction. Human immunodeficiency virus (HIV) infected patients are at increased risk of cardiovascular disease (CVD). Multidetector computed tomography (MDCT) stratifies cardiovascular risk in asymptomatic patients with subclinical atherosclerosis. The aim of this study was to determine the ability of MCTD and clinical and laboratory parameters to assess subclinical CVD progression in HIV patients. Material and methods. Prospective longitudinal cohort study of patients with at least 10 years of HIV infection and 5 years of antiretroviral therapy history, low cardiovascular risk and monitored for 6 years (2015–2021). All patients underwent clinical assessment, blood analysis, carotid ultrasound, and gated MDCT in 2015 and 2021. Results. Sixty-three patients (63.5% male) with a mean age of 49.9 years (standard deviation [SD], 10.5) were included in 2015; 63 of them were followed until 2021. Comparing the results from 2015 with those from 2021, Systematic Coronary Risk Estimation-2 (SCORE2) was 2.9% (SD, 2.1) vs. 4.4% (SD,3.1); Multi-Ethnic Study of Atherosclerosis score (MESA risk) was 3.4 (SD 5.8) vs. 6.0 (SD 8.6); coronary artery calcification CAC) score >100 was 11.1% vs. 25.4% (P < 0.05); and 11% vs. 27% had carotid plaques (P = 0.03). Conclusions. After six years of follow-up, an increase in SCORE2, carotid plaques, CAC scoring and MESA risk was observed. MDCT findings, along with other clinical and laboratory parameters, could play an important role as a marker of CVD progression in the evaluation of patients with HIV and low cardiovascular risk.

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Section: Discussionmentioning

confidence: 99%

Progression of subclinical cardiovascular disease in patients with HIV

Fayos,

Arnaiz de las Revillas,

González Quintanilla

et al. 2024

Rev Esp Quimioter

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“…All these studies indicated a substantially higher CVD event rate in patients with elevated ESR levels. Besides ESR, studies have also suggested the use of other popular RA-specific inflammatory markers such as CRP, or hsCRP, and IL-6 for the improvement in the CVD risk assessment [ 37 , 85 , 101 , 102 ]. Furthermore, these RA-specific inflammatory markers are also associated with the annual progression of cIMT [ 38 , 97 , 103 – 105 ], which is a prominent surrogate marker of cardiovascular events.…”

Section: Carotid Ultrasound Atherosclerosis Imaging For Cvd Risk Assementioning

confidence: 99%

Cardiovascular risk assessment in patients with rheumatoid arthritis using carotid ultrasound B-mode imaging

Jamthikar

Gupta

Puvvula³

et al. 2020

Rheumatol Int

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Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease that affects synovial joints and has various extraarticular manifestations, including atherosclerotic cardiovascular disease (CVD). Patients with RA experience a higher risk of CVD, leading to increased morbidity and mortality. Inflammation is a common phenomenon in RA and CVD. The pathophysiological association between these diseases is still not clear, and, thus, the risk assessment and detection of CVD in such patients is of clinical importance. Recently, artificial intelligence (AI) has gained prominence in advancing healthcare and, therefore, may further help to investigate the RA-CVD association. There are three aims of this review: (1) to summarize the three pathophysiological pathways that link RA to CVD; (2) to identify several traditional and carotid ultrasound image-based CVD risk calculators useful for RA patients, and (3) to understand the role of artificial intelligence in CVD risk assessment in RA patients. Our search strategy involves extensively searches in PubMed and Web of Science databases using search terms associated with CVD risk assessment in RA patients. A total of 120 peer-reviewed articles were screened for this review. We conclude that (a) two of the three pathways directly affect the atherosclerotic process, leading to heart injury, (b) carotid ultrasound image-based calculators have shown superior performance compared with conventional calculators, and (c) AI-based technologies in CVD risk assessment in RA patients are aggressively being adapted for routine practice of RA patients.

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“…The erythrocyte sedimentation rate (ESR) is standardized, accurate, and generally available and reflects the plasma concentration of acute response proteins, referred to as a compound measure of both immunoglobulins and inflammation. Although several clinical studies confirmed that ESR levels were positively correlated with the progression of atherosclerosis and increased risk of coronary heart disease mortality [10][11][12], these findings have not yet been corroborated in patients admitted for STEMI and multivessel diseases. To date, there is only one study indicating an independent association of ESR with the prognosis of STEMI [13].…”

Section: Introductionmentioning

confidence: 95%

Prognostic values of the SYNTAX score II and the erythrocyte sedimentation rate on long-term clinical outcomes in STEMI patients with multivessel disease: a retrospective cohort study

Zhang

Wang

et al. 2020

BMC Cardiovasc Disord

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Background There is a paucity of evidence on the combination of the SYNTAX score II (SSII) and erythrocyte sedimentation rate (ESR) in assessing the long-term prognosis of patients with ST-elevated myocardial infarction (STEMI) and multivessel disease. The objective of this study was to investigate whether the ESR could enhance the predictive value of SSII on the long-term prognosis of STEMI patients. Methods A retrospective cohort study involving 483 STEMI and multivessel disease subjects receiving primary percutaneous coronary intervention was conducted. Major adverse cardiovascular events (MACE) included cardiovascular death, acute heart failure, recurrent myocardial infarction, revascularization, and nonfatal stroke. The predicted values of different models were estimated by a likelihood ratio test, Akaike’s information criteria (AIC), receiver operating characteristic (ROC) curves, net reclassification improvement (NRI), and integrated discrimination improvement (IDI). Results During the follow-up period of up to 52 months, both the SSII and ESR were independently associated with MACE (hazard ratio [HR] = 1.032, p < 0.001; and HR = 1.021, p < 0.001, respectively). The likelihood test indicated that ESR could improve the prognostic model containing SSII (p < 0.001), while the combined model of SSII and ESR attained a lower AIC (p < 0.001). The area under the ROC curve of the combined model containing SSII and ESR increased by 0.05 (p = 0.04) compared to that of the model with SSII alone. The net reclassification and integrated discrimination of the SSII alone model improved significantly with ESR (NRI = 0.0319, p < 0.001; IDI = 0.0334, p < 0.001). Conclusions The prognostic model containing SSII, which is an independent risk factor of MACE, had a significantly enhanced predictive probability with the addition of ESR.

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ESR rate can be a marker for coronary artery disease

Cited by 6 publications

References 7 publications

Progression of subclinical cardiovascular disease in patients with HIV

Progression of subclinical cardiovascular disease in patients with HIV

Cardiovascular risk assessment in patients with rheumatoid arthritis using carotid ultrasound B-mode imaging

Prognostic values of the SYNTAX score II and the erythrocyte sedimentation rate on long-term clinical outcomes in STEMI patients with multivessel disease: a retrospective cohort study

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