Essential oil ofCroton ovalifolius Vahl from Venezuela

Meccia, Gina; Rojas, Luis; Rosquete, Carmelo; Feliciano, Arturo San

doi:10.1002/1099-1026(200005/06)15:3<144::aid-ffj882>3.0.co;2-c

Cited by 17 publications

(7 citation statements)

References 14 publications

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“…30 Another species with volatile oil containing predominantly sesquiterpenes (caryophyllene, caryophyllene oxide, germacrenes, cadinol, spathulenol) is the Venezuelan C. ovalifolius Vahl. 104 Leaves of C. zambesicus have volatile oil containing mostly sesquiterpenes (β-caryophyllene, caryophyllene oxide and α-copaene), monoterpenes (linalool and β-pinene) and smaller amounts of diterpenes (trachylobanes, isopimaranes and kaurenes). …”

Section: Volatile Oils and Their Constituentssupporting

confidence: 59%

Traditional uses, chemistry and pharmacology of Croton species (Euphorbiaceae)

Salatino¹,

Salatino²,

Negri³

2007

J. Braz. Chem. Soc.

401

320

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Croton é um gênero de Euphorbiaceae com cerca de 1300 espécies, amplamente distribuídas em regiões tropicais do Novo e Velho Mundos. Várias espécies há muito tempo desempenham papel importante nos usos tradicionais de plantas medicinais na África, Ásia e América do Sul. Tais usos incluem tratamento de câncer, constipação intestinal, diarréia e outros problemas digestivos, diabetes, feridas externas, febre, hipercolesterolemia, hipertensão, inflamação, vermes intestinais, malária, dor, úlceras e obesidade. Várias espécies de Croton têm um látex vermelho que contém, em algumas espécies, pró-antocianidinas e/ou alcalóides. Os alcalóides de Croton são a taspina ou substâncias relacionadas a benzilisoquinolinas. Os diterpenos são muito comuns em Croton, correspondendo a clerodanos, cembranóides, halimanos, cauranos, labdanos, ésteres do forbol, traquilobanos e sarcopetalanos. Algumas espécies são aromáticas, devido à presença de óleos voláteis. Representantes de novas classes de substâncias (fenilbutanóides, alcalóides glutarimidínicos e diterpenos sarcopetalanos) têm sido isoladas de espécies de Croton. Enquanto laticíferos têm sido descritos em espécies de Croton, até o momento não há estudos anatômicos sobre estruturas secretoras de óleos voláteis. Parece haver afinidades químicas no gênero relacionadas à geografia, agrupando espécies com (i) cauranos e/ou labdanos, (ii) traquilobanos e (iii) alcalóides. Os ensaios farmacológicos freqüentemente vêm corroborando os usos tradicionais de espécies de Croton. Grande parte dos ensaios farmacológicos trata do clerodano trans-desidrocrotonina, envolvendo uma grande diversidade de efeitos, incluindo hipolipidêmico, hipoglicêmico, antiestrogênico e anticâncer. Efeitos citotóxicos também vêm sendo observados em ensaios com alcalóides (taspina) e com diterpenóides secocaurenos, labdanos e cembranóides. Vários outros efeitos de substâncias de Croton têm sido relatados, incluindo anti-hipertensivos, antiinflamatórios, antimaláricos, antimicrobianos, antiespasmódicos, antiulcerogênicos, antivirais e mio-relaxantes.Croton is a genus of Euphorbiaceae comprising around 1,300 species, widespread in tropical regions of the Old and New Worlds. Several species have a long role in the traditional use of medicinal plants in Africa, Asia and South America. Popular uses include treatment of cancer, constipation, diabetes, digestive problems, dysentery, external wounds, fever, hypercholesterolemia, hypertension, inflammation, intestinal worms, malaria, pain, ulcers and weight-loss. Several species of Croton have a red sap, in some species containing proanthocyanidins and/or alkaloids. The latter may be taspine or some of several benzylisoquinoline-like compounds. Diterpenes are very common in Croton, corresponding to clerodanes, cembranoid, halimanes, kauranes, labdanes, phorbol esters, trachylobanes and sarcopetalanes. Some species are aromatic due to the possession of volatile oils. Representatives of new classes of compounds (phenylbutanoids, glutarimide alkaloids, sarcopetalane diterpen...

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Section: Volatile Oils and Their Constituentssupporting

confidence: 59%

Traditional uses, chemistry and pharmacology of Croton species (Euphorbiaceae)

Salatino¹,

Salatino²,

Negri³

2007

J. Braz. Chem. Soc.

401

320

View full text Add to dashboard Cite

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“…Smaller amounts of others compounds present in the leaf oil were: methyl eugenol (10.6%), β-caryophyllene (4.5%), (Z)-anethole (4.7%) and (E)-methyl isoeugenol (4.7%). The oils of various species of Croton are characterized by the predominance of chemical constituents of the class of monoterpenes and sesquiterpenes as principal components (25). Phenyl propanoids, like anethole and eugenol-derivatives, which are common in oils of fennel, basil and clove have been reported as principal components of the oils of others Croton species found in different parts of the world like for example: C. zehntneri and C. nepetaefolius, in Brazil (26); C. malambo and Croton cuneatus in Venezuela (27); Croton pseudoniveus and C suberosus in Mexico (28).…”

Section: Resultsmentioning

confidence: 98%

Composition and Insecticidal Activity of the Essential Oil ofCroton grewioidesBaill. against Mexican Bean Weevil (Zabrotes subfasciatusBoheman)

Silva¹,

Zago²,

Júnior³

et al. 2008

Journal of Essential Oil Research

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The essential oils of leaves and stems of Croton grewioides Baill. of the "agreste" region of Pernambuco, Brazil, were obtained by hydrodistillation and analyzed by GC and GC/MS. Twenty-two components were identified, which represented 99.8% and 98.6% of the total constituents in the leaf and stem oil, respectively. Croton grewioides produced an oil with a predominance of phenylpropanoid compounds, whose principal component was (E)-anethole (65.5% in the leaf and 47.8% in the stem). Other major components found in the leaf oil were methyl eugenol (10.6%) and (E)-methyl isoeugenol (4.7%). Other components identified in the stem oil were (E)-methyl isoeugenol (30.0%), cadalene (8.4%) and methyl eugenol (4.6%). The insecticidal activity of C. grewioides was evaluated against Mexican bean weevils, Zabrotes subfaciatus (Boheman) resulting in a LC 50 for the leaf oil, which was 3.4 times less than that obtained from the stem oil.

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“…27 The essential oil from Croton ovalifolius contains 6.0% spathulenol and 5.2% caryophyllene oxide. 28 We find spathulenol as the major compound in Croton rosmarinoides 29 at 13.8% and in Croton argyrophylloides 30 at 20.3%. Among the major compounds isolated from Croton flavens, 31 spathulenol reached 3-5%.…”

Section: Resultsmentioning

confidence: 77%

Velamo do Campo: Its Volatile Constituents, Secretory Elements, and Biological Activity

Babili

Roques

Haddioui

et al. 2012

Journal of Medicinal Food

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The volatile components from Croton campestris root bark were localized by an anatomical study and analyzed by gas chromatography-mass spectrometry for the first time. The roots of this plant showed secretory cells. These volatile constituents, isolated from the dichloromethane extract by hydrodistillation, were analyzed by gas chromatography-mass spectrometry. We found 69 components. They were characterized, and the major constituents of crude oil root barks were spathulenol (23.3%) and borneol (18.7%). Growth inhibitory activity of the active compounds in solution was evaluated by measuring minimal inhibitory concentrations using a broth micromethod. The minimal inhibitory concentration of root bark volatile constituents was 1.56 μg/mL for Staphylococcus aureus, 3.125 μg/mL for Candida albicans, and 6.25 μg/mL for Aspergillusniger.

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Essential oil ofCroton ovalifolius Vahl from Venezuela

Cited by 17 publications

References 14 publications

Traditional uses, chemistry and pharmacology of Croton species (Euphorbiaceae)

Traditional uses, chemistry and pharmacology of Croton species (Euphorbiaceae)

Composition and Insecticidal Activity of the Essential Oil ofCroton grewioidesBaill. against Mexican Bean Weevil (Zabrotes subfasciatusBoheman)

Velamo do Campo: Its Volatile Constituents, Secretory Elements, and Biological Activity

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