Essential oil ofDittrichia viscosa ssp.viscosa: analysis by13C-NMR and antimicrobial activity

Abstract

The essential oil of Dittrichia viscosa ssp. viscosa from Corsica was investigated by GC and 13 C-NMR spectroscopy. First, the sample was submitted to an acido-basic partition and the neutral part was repeatedly chromatographed. The analysis of all the fractions led to the identification of 71 components. The main constituents were fokienol (21.1%), (E)-nerolidol (8.6%) and eudesm-6-en-4α α α α α-ol (6.2%). The antimicrobial activity of the neutral and acidic fractions were investigated. While the neutral part appeared to be inactive, the acidic part was active against all the tested microorganisms. The highest activity was obtained against Staphylococcus epidermidis, Streptococcus foecalis and Proteus vulgaris.

Susceptibility of Helicobacter pylori to essential oil of Dittrichia viscosa subsp. revoluta

“…viscosa collected in Portugal was also subjected to studies in order to elucidate its ability to prevent H. pylori growth (Silva et al, 2005). The investigators concluded that the chemical composition of the oil isolated from plants collected in Portugal was closer to that previously reported (Camacho et al, 2000) for the oil obtained from plants from Spain (Province of Jaénz) and for that from Corsica (Blanc et al, 2006), mainly in the presence of the major components fokienol and (E)nerolidol. Moreover in that study, a small amount of essential oil of D. viscosa subsp.…”

“…revoluta representing 15% of the total oil of the inflorescences. The presence of costic acid, isocostic acid and 4-en-ilicic acid were reported by Blanc et al (2006Blanc et al ( , 2005Blanc et al ( , 2004 for D. viscosa ssp. viscosa and Inula graveolens from Corsica.…”

Essential oil of AlgerianInula viscosaleaves

“…Among the small quantity of oxygenated monoterpenes there were 0.14 % eugenol and traces of cineole and p-mentha-1,5-dien-8-ol. There are two main compounds composing 13 and Spain (Jaèn ) 14 , 12-Carboxydeudesma-3,11(13)diene (isocostic acid) dominate the composition of Algerian I. viscosa essential oils as well as in Apulia southern Italy 16 .…”

“…From the ancient times, this medicinal plant has been used for several therapeutic purposes: antimicrobial 4 , treatment of wounds 5 , muscle relaxant 6 , anti-inflammatory 7,8 , antifungal 9 , cardiovascular and digestive 10,11 . The essential oil composition of some Inula viscosa species has been the subject of several investigations [12][13][14][15][16] . Sesquiterpenes lactones, flavonoïds, eudesmanes and triterpenoïds are typical in this specie [17][18][19][20][21] .…”

Additional insights from very‐high‐resolution 13C NMR spectra of long‐chain n‐alkanes

“…Waxy long‐chain n ‐alkanes are also used by nature. For example, they provide the protective coating on plant leaves (especially cacti), are used by flowers to attract insects to pollinate, are found in insect pheromones, and a plant essential oil …”