Essential oil variation in the populations of<i>Artemisia spicigera</i>from northwest of Iran: Chemical composition and antibacterial activity

Chehregani, Abdolkarim; Atri, Morteza; Yousefi, Somayeh; Albooyeh, Zahra; Mohsenzadeh, Farshid

doi:10.3109/13880209.2012.717631

Cited by 14 publications

(10 citation statements)

References 36 publications

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“…It helps treat nasal and sinus inflammation and secretions in acute nonpurulent rhinosinusitis and is used as a nasal decongestant and cough suppressant . It is anti‐fungal including activity against onychomycosis, anti‐cancer, antibacterial, anti‐tuberculosis, insecticidal, and inhibits cholesterol synthesis …”

Section: Terpenes (Terpenoids)mentioning

confidence: 99%

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science

2018

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There is accumulating evidence for various therapeutic benefits of cannabis/cannabinoids, especially in the treatment of pain, which may also apply to the treatment of migraine and headache. There is also supporting evidence that cannabis may assist in opioid detoxification and weaning, thus making it a potential weapon in battling the opioid epidemic. Cannabis science is a rapidly evolving medical sector and industry with increasingly regulated production standards. Further research is anticipated to optimize breeding of strain-specific synergistic ratios of cannabinoids, terpenes, and other phytochemicals for predictable user effects, characteristics, and improved symptom and disease-targeted therapies.

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Section: Terpenes (Terpenoids)mentioning

confidence: 99%

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science

2018

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“…Phenolic compounds are the major antioxidants of some herbal extracts like Propolis against Cryptosporidium ( 28 ). Antibacterial and antifungal activity of A. spicigera is related to high levels of these compounds ( 11 , 14 ), found in this study as major compounds in As –EtOH extract. Therefore the activity of A. spicigera ethanolic extract against Cryptosporidium may be owing to its rich contents of phenolic compounds and flavonoids, demonstrated to be responsible for the anti-protozoal effect by enhancing oxidative defense mechanisms.…”

Section: Discussionmentioning

confidence: 51%

“…In A. abrotanum L., a range of several flavonoids, coumarins and sesquiterpenes have been detected ( 7 ). In essential oil and extracts of A. spicigera, significant amounts of phenol, flavonoids contents have been detected ( 14 , 15 , 44 ). A positive result was seen between total phenol and flavonoid levels of samples and the free radical scavenging activity potential ( 44 , 28 ).…”

Section: Discussionmentioning

confidence: 99%

“…Pharmacological researches have indicated antimalarial ( 7 , 9 ), antibacterial ( 10 ), antifungal ( 11 ), antioxidant ( 10 ), nematocidal, and cesticidal activities ( 12 , 13 ), for Artemisia species. Known as «dermane ye sonbolei〉〉 in Persian , A. spicigera C. Koch is growing in Armenia, Middle Anatolia, Northwest and North of Iran ( 14 ). This species has traditionally been used in medicine.…”

Section: Introductionmentioning

confidence: 99%

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The Protective Effect of Artemisia spicigera Ethanolic Extract against Cryptosporidium parvum Infection in Immunosuppressed Mice

Shahbazi¹,

Nematollahi²,

Arshadi³

et al. 2021

IJPA

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Background: A specific treatment has not yet developed for cryptosporidiosis, and some of the used drugs had side effects in immunodeficient patients. The goal of an appropriate remedy is to remove symptoms and improve immune responses in hosts. The current study was designed to evaluate the therapeutic efficacy of Artemisia spicigera ethanolic extract in experimentally infected immunosuppressed mice. Methods: Thirty six NMRI mice, 4-6 wk old, were randomly divided into six equal groups. C1: uninfected, treated control; C2: infected, untreated control; T1, T2, T3, and P: infected, treated with 0.2, 2, and 20 mg/ml extract, and 5mg/ml paromomycin, respectively. Mice were experimentally infected by oral administration of 104 oocysts/animal of Cryptosporidium parvum and treated orally for eight days per 12h, starting 12h before experimental infection. The presence of oocyst shedding, weight gain/loss, and the histopathology of ileum sections were examined. Results: Results revealed that oocyst shedding was significantly (P<0.05) reduced in treatment groups. There was no significant difference between the mean of weight gain/loss in the infected control and treated groups. Histopathological analysis of ileum sections further supported the parasitological findings. Conclusion: Artemisia spicigera had acceptable efficacy as a therapeutic agent for cryptosporidiosis.

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“…and Pseudomonas aeruginosa [27]. The essential oil of Artemisia spicigera represented a powerful antibacterial activity against Citrobacter amalonaficus, Escherichia coli, Enterobacter aerogenes, Serratia marcescens, and Staphylococcus aureus [28]. Methanolic extract of Withania somnifera leaves exhibited a strong activity against Citrobacter freundii, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Klebsiella pneumoniae [29].…”

Section: Discussionmentioning

confidence: 99%

Effects of Lonicera japonica Flower Bud Extract on Citrobacter rodentium-Induced Digestive Tract Infection

Minami

Makino

2020

Medicines

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Background: Although antibiotic therapy is currently a gold standard for bacterial infections, it is not used for severe diseases like enterohemorrhagic Escherichia coli, in which the Shiga toxin is overproduced by antibiotic action. The Lonicera japonica flower bud (LJF) is an herbal component used against purulent diseases in traditional Japanese and Chinese medicine. We investigated the effects of LJF extract (LJFE) on Citrobacter rodentium-induced digestive tract infection in a mouse model. Methods:Citrobacter rodentium and LJFE were orally administered to C57BL/6 mice. The survival rate and bacterial colonization in the large intestine, mesenteric lymph node, and blood of mice were evaluated. Cytokines secreted from intraperitoneal macrophages of LJFE-treated mice were measured using ELISA. Moreover, the phagocytic activity of intraperitoneal macrophages against Citrobacter rodentium was compared between LJFE- or chlorogenic acid (CGA)-treated mice. Results: LJFE significantly increased the survival rate and decreased Citrobacter rodentium colonization in mice. Moreover, the values of tumor necrosis factor-α, interleukin-1β, and interferon-γ secreted from macrophages were increased following LJFE treatment. While macrophages of LJFE-treated mice showed a significant phagocytic activity, macrophages of CGA-treated mice only showed a phagocytic tendency. Conclusions: LJF may be useful for treating Citrobacter rodentium-induced digestive tract infection.

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Essential oil variation in the populations ofArtemisia spicigerafrom northwest of Iran: Chemical composition and antibacterial activity

Cited by 14 publications

References 36 publications

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science

The Protective Effect of Artemisia spicigera Ethanolic Extract against Cryptosporidium parvum Infection in Immunosuppressed Mice

Effects of Lonicera japonica Flower Bud Extract on Citrobacter rodentium-Induced Digestive Tract Infection

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