Essential oils and related products

Gilbertson, Gilbert.; Koenig, Roman T.

doi:10.1021/ac00228a006

Cited by 9 publications

(4 citation statements)

References 79 publications

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“…Sesquiterpenes, the largest class of terpenes, consist of three isoprene units and are represented by the molecular formula of C 15 H 24 ( dos Santos Franciscato et al., 2022 ). Some of the important known sesquiterpenes are: bisabolol found in Matricaria recutita ( Herrera et al., 2022 ); chamazulene found in Artemisia absinthium ( Mohammed, 2022 ); farnesol and cumin found in Vachellia farnesiana ; guaiazulene found in Cuminum cyminum ( Gilbertson and Koenig, 1981 ); and dicarabrol found in Carpesium abrotanoides L. (Asteraceae) and Lactarius indigo ( Jie-Wei et al., 2021 ).…”

Section: Secondary Metabolitesmentioning

confidence: 99%

Production of secondary metabolites using tissue culture-based biotechnological applications

et al. 2023

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Plants are the sources of many bioactive secondary metabolites which are present in plant organs including leaves, stems, roots, and flowers. Although they provide advantages to the plants in many cases, they are not necessary for metabolisms related to growth, development, and reproduction. They are specific to plant species and are precursor substances, which can be modified for generations of various compounds in different plant species. Secondary metabolites are used in many industries, including dye, food processing and cosmetic industries, and in agricultural control as well as being used as pharmaceutical raw materials by humans. For this reason, the demand is high; therefore, they are needed to be obtained in large volumes and the large productions can be achieved using biotechnological methods in addition to production, being done with classical methods. For this, plant biotechnology can be put in action through using different methods. The most important of these methods include tissue culture and gene transfer. The genetically modified plants are agriculturally more productive and are commercially more effective and are valuable tools for industrial and medical purposes as well as being the sources of many secondary metabolites of therapeutic importance. With plant tissue culture applications, which are also the first step in obtaining transgenic plants with having desirable characteristics, it is possible to produce specific secondary metabolites in large-scale through using whole plants or using specific tissues of these plants in laboratory conditions. Currently, many studies are going on this subject, and some of them receiving attention are found to be taken place in plant biotechnology and having promising applications. In this work, particularly benefits of secondary metabolites, and their productions through tissue culture-based biotechnological applications are discussed using literature with presence of current studies.

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Section: Secondary Metabolitesmentioning

confidence: 99%

Production of secondary metabolites using tissue culture-based biotechnological applications

et al. 2023

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“…In Chinese pharmacopoeia [2], GC acts as an official identification and quality control method for some traditional Chinese medicines. [16] In antibacterial and antirheumatism plant medicines, terpenoids [19][20][21] are the most typical kind of volatile active components. As listed in Table 2, a lot of literature is focused on the separation and determination of these compounds [22][23][24][25][26][27][28][29][30][31][32][33][34][35], and a comprehensive review on the separation of cardioactive and antibacterial terpenoids from some Salvia species was presented by Ulubelen reasently.…”

Section: Gas Chromatography (Gc) Gas Chromatography-mass Spectrometrmentioning

confidence: 99%

Separation methods for antibacterial and antirheumatism agents in plant medicines

Wen

Liu

et al. 2004

Journal of Chromatography B

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“…The beneficial effects are related to different classes of therapeutically interesting ingredients such as essential oil components, flavonoids, and coumarin derivatives [1, 5, and 6]. The chamomile essential oils, which are of the greatest importance among the bioactive constituents [7], consist of many active compounds such as (-)-alpha-bisabolol, chamazulene (artefact of matricine by steam distillation), (-)-alpha-bisabolol oxide A and B, (-)-alpha-bisabolone oxide A, spiroethers (cis-and trans-en-yn-dicycloether), and sesquiterpenes [8]. The chamomile volatile oils showed antimicrobial activity against certain species of bacteria, fungi and viruses in vitro [9], however, Gram-positive bacteria were found more susceptible than Gram-negative ones [10].…”

Section: Introductionmentioning

confidence: 99%

Separation and Identification of Antibacterial Chamomile Components Using OPLC, Bioautography and GC-MS

Móricz¹,

Szarka²,

Ott³

et al. 2012

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Components of 50% ethanolic chamomile (Matricaria recutica L.) flower extract, previously found antibacterial in a TLC-bioautographic study, were separated and isolated by the use of on-line OPLC, which consisted of an OPLC 50 BS system, an on-line coupled flow-through UV detector, and a manual fraction collector. The collected peaks were investigated by GC-MS analysis and by TLC re-chromatography with subsequent visualization, performed after use of the vanillin-sulphuric acid reagent, or under UV illumination, or applying bioautographic detection. The main compounds of the collected 11 fractions were identified by GC-MS. The results showed that the antibacterial effect of 50% ethanolic extract of chamomile is ascribable to cis-, trans-spiroethers, and the coumarins like herniarin and umbelliferone. Separation and identification of antibacterial chamomile components 3 INTRODUCTIONThere is an increased demand to discover new, effective, easy-to-obtain natural medicinal substances. Chamomile (Matricaria recutica L.) is a very familiar and widely used herb in traditional folk medicine. The flower is a common ingredient of herbal teas because it contains substances which have anti-inflammatory, sedative, analgesic, antispasmodic, antioxidant and antimicrobial properties [1][2][3][4]. The beneficial effects are related to different classes of therapeutically interesting ingredients such as essential oil components, flavonoids, and coumarin derivatives [1, 5, and 6]. The chamomile essential oils, which are of the greatest importance among the bioactive constituents [7], consist of many active compounds such as (-)-alpha-bisabolol, chamazulene (artefact of matricine by steam distillation), (-)-alpha-bisabolol oxide A and B, (-)-alpha-bisabolone oxide A, spiroethers (cis-and trans-en-yn-dicycloether), and sesquiterpenes [8]. The chamomile volatile oils showed antimicrobial activity against certain species of bacteria, fungi and viruses in vitro [9], however, Gram-positive bacteria were found more susceptible than Gram-negative ones [10]. The chamomile oils were effective e.g. [17,18]. Herniarin, the main coumarin component in chamomile, is a more effective antimicrobial agent than umbelliferone, which may be realized by its demethylation [19]. Umbelliferone has been described as a stress metabolite in M. recutita. The amount of umbelliferone characteristically, while that of herniarin mildly rose in the plant after biotic and abiotic stress influences [6,20]. It was also observed that chamomile oil component (Z)-spiroether was lowered after abiotic stress, but increased in the case of biotic stress [6]. Searching for bioactive natural products requires appropriate bioassays, focused on the desired activity (e.g. antifungal, antibacterial). Layer chromatography is an ideal technical solution for the screening of drug ingredients, because of high-throughput, low cost, easy maintenance and selectivity of detection reagents [21]. Direct bioautography [22][23][24][25][26], linking the separation with biological det...

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Essential oils and related products

Cited by 9 publications

References 79 publications

Production of secondary metabolites using tissue culture-based biotechnological applications

Production of secondary metabolites using tissue culture-based biotechnological applications

Separation methods for antibacterial and antirheumatism agents in plant medicines

Separation and Identification of Antibacterial Chamomile Components Using OPLC, Bioautography and GC-MS

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