Essential Oils of Lavandula stoechas subsp. luisieri as Antifungal Agent against Fungi from Strawberry Tree Fruit

Domingues, Joana; Delgado, Fernanda; Gonçalves, José Carlos; Pintado, Cristina M. B. S.

doi:10.17265/2328-2150/2021.03.002

Cited by 4 publications

(11 citation statements)

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“…The chemical composition of EOLS has been investigated in various Mediterranean countries (Algeria, Greece, France, Tunisia, Italy, and Turkey), with varying results (Table 3). The aromatic compounds of lavender identified in this analysis were both comparable and divergent to those recorded in previous research [18][19][20][21][22][23][24][25][26][27][28][29][30]. For example, our findings are consistent with those of Chebil et al [40], who found that linalool and linalyl acetate were the most abundant oxygenated terpenes in Tunisian EO.…”

Section: Methodssupporting

confidence: 88%

Topical Emulsion Containing Lavandula stoechas Essential Oil as a Therapeutic Agent for Cutaneous Wound Healing

Boukhatem

Chader²,

Houche

et al. 2021

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Background and objectives: The present research was designed to evaluate the chemical composition of Lavandula stoechas essential oil (EOLS) as well as the in vivo wound-healing property. The chemical composition of EOLS was identified by gas chromatography mass spectrometry. Nineteen compounds of EOLS were reported. Linalool was identified as the major chemical compound (24.87%), followed by linalyl acetate (19.10%). EOLS showed a high content of oxygenated compounds (63.54%). In vivo wound healing activity of the topical cream prepared from EOLS (0.5% w/w) was assessed using a circular excision wound model. The wound area (mm2) in all animal groups was estimated and measured on day 0, 4, 8, 11, and 16. Results: The EOLS formulation cream (0.5% v/w) showed the highest effect on wound models when compared to reference Madecassol® (Asiaticoside). On days 4, 11, and 16, wound contractions were 26.4%, 78%, and 96.3% for the EOLS-treated group, and 8.5%, 64.1%, and 86.1% for the vehicle cream-treated group. Animals treated with EOLS cream showed a significant decrease in the epithelization period, wound area, and scar thickness, whereas the rate of wound contraction significantly increased. This is the first such report to be published. Histological analyses were also consistent with the results of the excision experimental method. Treatment with EOLS cream formulation resulted in decreased inflammation and an increased rate of tissue perfusion and proliferation as well as remodeling, along with re-epithelization. Conclusions: Our results support the use of EOLS in the development of pharmaceuticals for the management of wounds, and/or inflammatory-related diseases. Additional studies are needed to elucidate and explain the exact mechanism of its pharmacological activity.

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Section: Methodssupporting

confidence: 88%

Topical Emulsion Containing Lavandula stoechas Essential Oil as a Therapeutic Agent for Cutaneous Wound Healing

Boukhatem

Chader²,

Houche

et al. 2021

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“…Concerning the main compounds of L. stoechas subsp. luisieri essential oil from the Iberian Peninsula, camphor (1.1–74.4%), trans -α-necrodyl acetate (1.8–48.2%), 2,3,4,4-tetramethyl-5-methylcyclopenten-2-enone (2–38%), fenchone (0.1–22%), and 1,8-cineole (1.3–21%) have been reported as the major constituents [ 5 , 14 , 19 , 20 , 25 , 36 , 63 , 70 , 71 , 72 , 73 , 74 , 75 , 76 ]. In most studies of plants from Portugal, the main chemical compounds present in the essential oil of L. stoechas subsp.…”

Section: Secondary Metabolites From Lavandula Sect...mentioning

confidence: 99%

“…In the first region, the essential oil was characterized by the presence of trans -α-necrodyl acetate (17%), followed by trans -α-necrodol (7%) and 1,8-cineole (6%), while the main compounds of the essential oils from southern plants were 1,8-cineole (34%) and fenchone (18%), and the concentration of necrodane compounds was very low (around 3% of trans -α-necrodyl acetate) [ 36 ]. Domingues et al reported a high content of trans -α-necrodyl acetate (27%), trans -α-necrodol (13%), lavandulyl acetate (7%), and linalool (6%) in the flowering phenological stage, while the essential oil of the dormancy phase had a lower necrodane content; however, 5-methylene-2,3,4,4-tetramethylcyclopenten-2-enone (11%), fenchone (6%), 1,8-cineole (5%), and camphor (3%) concentrations were higher than those observed in the essential oil obtained from the flowering stage [ 19 ]. Regarding the reported studies, differences in the concentration of necrodane compounds are frequent, and it has been reported that essential oils with higher amounts of these compounds have more potent biological activities [ 25 , 36 , 72 ].…”

Section: Secondary Metabolites From Lavandula Sect...mentioning

confidence: 99%

“…In recent years, many of these traditional uses have been validated in scientific-based studies, and several volatile and non-volatile compounds have been identified as promising lead compounds. For example, antibacterial, antifungal, anti-inflammatory, analgesic, carminative, antidepressant, and sedative properties have been pointed out, thus highlighting the beneficial potential of these species [ 19 , 20 , 21 , 22 , 23 ]. Moreover, in several countries, for example, Portugal, the number of distilleries has increased mainly due to the knowledge and interest of consumers in these natural products and their exceptional properties for human health.…”

Section: Introductionmentioning

confidence: 99%

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Mediterranean Lavenders from Section Stoechas: An Undervalued Source of Secondary Metabolites with Pharmacological Potential

et al. 2023

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Globally, climate change and wildfires are disrupting natural ecosystems, thus setting several endemic species at risk. The genus Lavandula is widely present in the Mediterranean region and its species, namely, those included in the section Stoechas, are valuable resources of active compounds with several biological assets. Since ancient times lavenders have been used in traditional medicine and for domestic purposes. These species are melliferous, decorative, and essential oil-producing plants with a high economic interest in the pharmaceutical, flavor, fragrance, and food industries. The essential oils of Lavandula section Stoechas are characterized by high amounts of 1,8-cineole, camphor, fenchone, and specifically for L. stoechas subsp. luisieri one of the major compounds is trans-α-necrodyl acetate. On the other hand, the diversity of non-volatile components like phenolic compounds, such as phenolic acids and flavonoids, make these species an important source of phytochemicals with pharmacological interest. Rosmarinic, caffeic, and salvianolic B acids are the major phenolic acids, and luteolin and eriodictyol-O-glucuronide are the main reported flavonoids. However, the concentration of these secondary metabolites is strongly affected by the plant’s phenological phase and varies in Lavandula sp. from different areas of origin. Indeed, lavender extracts have shown promising antioxidant, antimicrobial, anti-inflammatory, and anticancer properties as well as several other beneficial actions with potential for commercial applications. Despite several studies on the bioactive potential of lavenders from the section Stoechas, a systematized and updated review of their chemical profile is lacking. Therefore, we carried out the present review that gathers relevant information on the different types of secondary metabolites found in these species as well as their bioactive potential.

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“…Different activities of Lavandula spp. such as antioxidant (Yakoubi et al, 2021), cytotoxic (Siddiqui et al, 2020), antimicrobial (Leong et al, 2021), anti-acetylcholinesterase (Vairinhos & Miguel, 2020), antibacterial (Sayout et al, 2020), repellent (Huang et al, 2020), antifungal (Domingues et al, 2021), allelopathic (Nazemi et al, 2016) have been recorded recently.…”

Section: Introductionmentioning

confidence: 99%

Chemical components and insecticidal effects of essential oils from three lavender cultivars against adult Sitophilus granarius (L., 1758) (Coleoptera: Curculionidae)

Alkan¹,

Güzel²,

Akşit³

et al. 2021

Turkish Journal of Entomology

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Essential Oils of Lavandula stoechas subsp. luisieri as Antifungal Agent against Fungi from Strawberry Tree Fruit

Cited by 4 publications

References 0 publications

Topical Emulsion Containing Lavandula stoechas Essential Oil as a Therapeutic Agent for Cutaneous Wound Healing

Topical Emulsion Containing Lavandula stoechas Essential Oil as a Therapeutic Agent for Cutaneous Wound Healing

Mediterranean Lavenders from Section Stoechas: An Undervalued Source of Secondary Metabolites with Pharmacological Potential

Chemical components and insecticidal effects of essential oils from three lavender cultivars against adult Sitophilus granarius (L., 1758) (Coleoptera: Curculionidae)

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