Essentials of Medical Physiology

Sembulingam, Prema

doi:10.5005/jp/books/10283

Cited by 20 publications

(24 citation statements)

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“…Histological results showed hypertrophy and hyperplasia of cells of the medial prefrontal cortex in the test groups. Hyperplasia is indicated by an abnormal increase in the number of organic tissue, while hypertrophy is the increase in cell size 19 . These changes may be physiologic or pathologic, and usually result from increase demand, chronic inflammatory response, hormonal dysfunction or compensation for damage or disease elsewhere 20 , which may affect the function of the medial prefrontal cortex.…”

Section: Discussionmentioning

confidence: 99%

Chronic <i>Allium sativum</i> administration alters spontaneous alternation and cyto-architecture of medial prefrontal cortex of adult Wistar rats

Muonagolu¹,

Ekong²,

Edgaha³

2017

Internet Journal of Medical Update - EJOURNAL

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Intake of herbs and some of their constituents is reported to reduce risks of some diseases, with Allium sativum being one of such. This study was conducted to investigate the effects of Allium sativum extract on the medial prefrontal cortex and neurobehaviour of adult Wistar rats. Twenty-four male Wistar rats were divided into 4 groups (n = 6). Group 1 was the control and received distilled water placebo orally, while groups 2-4 received oral doses of 78 mg/kg, 156 mg/kg and 312 mg/kg Allium sativum extract for 28 days. On day 29, spontaneous alternation behavioural test was carried out, and immediately the rats were anaesthetized (50 mg/kg ketamine hydrochloride IP.) and perfusion-fixed with 10% buffered formalin. The whole brains were removed and the medial prefrontal cortex excised and processed for histomorphologic studies by haematoxylin and eosin, and cresyl fast violet techniques. Neurobehavioural test revealed less spontaneous alternation in 156 mg/kg Allium sativum group, while the prefrontal cortices of the test groups showed hypertrophy, hyperplasia, pyknosis, karyorrhexis, chromatolysis, loss of brain cellular membranes and Nissl substance. The 156 mg/kg Allium sativum group showed altered spontaneous alternation, while cellular pathologic changes were observed in the medial prefrontal cortex of these test groups in a dose dependent sequence.

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Section: Discussionmentioning

confidence: 99%

Chronic <i>Allium sativum</i> administration alters spontaneous alternation and cyto-architecture of medial prefrontal cortex of adult Wistar rats

Muonagolu¹,

Ekong²,

Edgaha³

2017

Internet Journal of Medical Update - EJOURNAL

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“…Normally, beta band power is prominently seen in a highly focused, agitated and attentive brain as in cases of problem solving or in fear, anxiety etc. whereas alpha and delta bands are mostly seen in calm and quiet brain [18]. These two types of pranayama are claimed to cool the body and counter-act the Pitta and body heat by regulating the body temperature and modifying the functions of important areas of the brain.…”

Section: Discussionmentioning

confidence: 99%

Impact of Sheetali and Sheetkari Pranayama on the Topographic Mapping of the Brain Waves

kshmi¹,

Ravindran²,

Sembulingam³

et al. 2014

iosrphr

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Pranayama is yogic breathing technique which is known to improve the physical and mental well-being. The tremendous impact of yoga on the functioning of nervous system, attenuation of stress and promotion of relaxation is well known. Sheetali and Sheetkari pranayama also produce similar effects but, in addition, they also cool down the body and the brain. However, the impact of these pranayama on electroencephalogram (EEG) is not explored so far. For this study, 20 male volunteers were recruited and divided into two equal groups namely yoga group (YG) who underwent the practice of these pranayama for two months and non-yoga group (NYG) who did not do any type of breathing technique. In both the groups, EEG topographic mapping was recorded and the results were compared. The mapping revealed an increase in the delta (red bands) and alpha band power (green bands) in the frontal and occipital regions and an increase in theta band power (yellow bands) in the frontal region with a marked decrease in beta band power (blue bands) almost throughout the entire hemisphere after two months' of Sheetali and Sheethkari pranayama practice indicating that the brain (mind) was calm and quiet in relaxed state with less anxiety.

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“…Dip-stick test reactions using urine reagent strips (Uro dip 10 A -ERBA diagnostics, Germany) were observed and recorded. Motion test, chest X ray, ECG and Echocardiogram were also done [13][14][15][16][17][22][23][24] .…”

Section: Evaluation Of Clinical Parametersmentioning

confidence: 99%

A Study on Siddha Urinary Diagnostic Methodology Neerkkuri and Neikkuri in Adhiratha Azhutham (Hypertension)

Banu¹,

Parvathy²,

Srinivasan³

et al. 2017

IJPCS

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Background:In Siddha system of medicine, diagnosis of the disease is based on Ennvagai thervukal (Eight fold examination), in which Neerkkuri Neikkuri (Urine examination) is one among them. It is an effective and sensitive measure for the diagnosis and prognosis of diseases. Objectives: This study was conducted to establish the validity of prognostic and diagnostic patterns of Neikkuri (Oil on urine sign)in hypertension patients and to assess the association between the Neikkuri patterns with respect to pH and specific gravity of urine. Methods and Material: Urine samples of 40 diagnosed patients of hypertension aged between 30 to 60 years were collected. Ten healthy volunteers were also selected as control group for comparison. Biochemical analysis was done in the urine samples with urine reagent strip to confirm health status of the subjects. A drop of sesame oil was dropped over 50 ml of each urine sample and behaviour (shape of the oil spread, direction and spread time) was observed. Results: Half of the samples of urine of hypertension patients showed circular shape initially and then vacuolating to turn out into a sieve pattern and in remaining others at least a single vacuolation amounting to ring pattern indicative of Pitham were shown. Also, the urine of the hypertension patients were characterised by straw colour and aromatic odour, absence of froth and specific gravity 1.003-1.010.Volume of urine voided ranged from 1-1.5 lit and pH between 5.1-6.In most of the cases the dissemination dynamics of oil drop observed were of slow spreading nature which indicates good prognosis. Conclusion: It is concluded that hypertension has got mixed prognosis which may indicate the variation in the amenability of hypertension to the treatment. The study explored the veracity of the investigative procedure in diagnosis and prognosis of hypertension with Neikkuri examination.

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Essentials of Medical Physiology

Cited by 20 publications

References 0 publications

Chronic <i>Allium sativum</i> administration alters spontaneous alternation and cyto-architecture of medial prefrontal cortex of adult Wistar rats

Chronic <i>Allium sativum</i> administration alters spontaneous alternation and cyto-architecture of medial prefrontal cortex of adult Wistar rats

Impact of Sheetali and Sheetkari Pranayama on the Topographic Mapping of the Brain Waves

A Study on Siddha Urinary Diagnostic Methodology Neerkkuri and Neikkuri in Adhiratha Azhutham (Hypertension)

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