Establishing a national strategy for shared research resources in biomedical sciences

Charalambakis, Naomi E.; Ambulos, Nicholas P.; Hockberger, Philip E.; Meyn, Susan M.; Bowen, Sara; Constable, Susan; Fisher, Nancy C.; Fletcher, Luellen; Kigenyi, Justine; Mundoma, Claudius; Ramirez-Aguilar, Kathryn A.; Vinard, Andrew; Winn, Mary E.; Mische, Sheenah M.

doi:10.1096/fj.202101393

Cited by 8 publications

(4 citation statements)

References 10 publications

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“…For research institutions to continue to succeed, publishing high-quality and innovative results as well as garnering extramural funding, core facilities will need to continue to evolve from strictly serviceoriented offerings to collaborative operations, merging the intellectual abilities of staff members with researchers to provide novel and innovative approaches to solve complex research questions. [27]…”

Section: Discussionmentioning

confidence: 99%

The Shared Core Resource as a Partner in Innovative Scientific Research: Illustration from an Academic Microscopy Imaging Center

et al. 2022

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Core facilities have a ubiquitous and increasingly valuable presence at research institutions. Although many shared cores were originally created to provide routine services and access to complex and expensive instrumentation for the research community, they are frequently called upon by investigators to design protocols and procedures to help answer complex research questions. For instance, shared microscopy resources are evolving from providing access to and training on complex imaging instruments to developing detailed innovative protocols and experimental strategies, including sample preparation techniques, staining, complex imaging parameters, and high-level image analyses. These approaches require close intellectual collaboration between core staff and research investigators to formulate and coordinate plans for protocol development suited to the research question. Herein, we provide an example of such coordinated collaboration between a shared microscopy facility and a team of scientists and clinician-investigators to approach a complex multiprobe immunostaining, imaging, and image analysis project investigating the tumor microenvironment from human breast cancer samples. Our hope is that this

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Section: Discussionmentioning

confidence: 99%

The Shared Core Resource as a Partner in Innovative Scientific Research: Illustration from an Academic Microscopy Imaging Center

et al. 2022

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“…[6] The task force also published a policy brief with recommendations for individual investigators, institutions, regional coalitions, and federal agencies on strategies and best approaches for positioning, investing, and sustaining SRRs. [7] FASEB ASEB Shared Research Resource task force roundtables (virtual)…”

Section: The Faseb Shared Research Resource Task Forcementioning

confidence: 99%

Strategies for Shared Research Resources for Enhancing Research Sustainability: Communicating Between Stakeholders and Managing Expectations to Maximize Value and Impact

Kigenyi¹,

Bowen²,

Constable³

et al. 2023

J Biomol Tech

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Shared research resources occupy a unique role in the scientific research landscape. Sometimes called core facilities, shared research resources provide instrumentation, services, and expertise to a wide range of researchers. With dedicated staff maintaining instruments, training users, and supporting collaborations, these resources are well situated to churn out reproducible high-quality data, lead research innovation, create efficiencies, and stimulate economic development all while driving down capital costs for institutions. That being said, in the high-paced disciplines of science with limited resources and competing priorities, these resources are often obligated to demonstrate their worth, especially beyond traditional service delivery models.How can shared research resources quantify and communicate their value and impact to stakeholders for optimal support and sustainability? For best approaches towards value proposition, it is important to understand the various stakeholders in the shared research resource ecosystem, including their needs, expectations, and value systems. This will in turn inform models of support and best approaches for planning, positioning, managing, evaluating, and improving shared research resource output to return the most value to all stakeholders involved. It is imperative that communication is tailored for each unique group of stakeholders, and terminology and expectations are managed accordingly. This work attempts to curate and share approaches and best practices toward this effort, gathered through available literature and focused engagement with various shared research resource stakeholders.

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“…A clear example of how funding agencies could take the lead in championing SRRs is outlined in a policy brief the Task Forced authored in the months following the release of the final report. The paper, Establishing a National Strategy for Shared Research Resources in Biomedical Sciences, [3] calls on the NIH to create an SRR Working Group within the Advisory Committee to the Director (ACD). As the primary advisory body to the Office of the Director, the ACD is a valuable oversight mechanism for providing policy and programmatic recommendations to the agency director.…”

Section: Section Ii: Role Of Stakeholders and Funding Agenciesmentioning

confidence: 99%

Research for the Future: An Overview of the FASEB Shared Research Resources Task Force’s Finding and Recommendations

Charalambakis¹

2022

J Biomol Tech

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The Federation of American Societies for Experimental Biology (FASEB) is composed of 28 member societies, representing over 115,000 individual scientists, including the Association of Biomedical Research Facilities and its members. As part of FASEB's mission to advance awareness and support of biological and biomedical research, the Federation remains committed to sustaining support for the resources that investigators use to conduct rigorous research.

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Establishing a national strategy for shared research resources in biomedical sciences

Cited by 8 publications

References 10 publications

The Shared Core Resource as a Partner in Innovative Scientific Research: Illustration from an Academic Microscopy Imaging Center

The Shared Core Resource as a Partner in Innovative Scientific Research: Illustration from an Academic Microscopy Imaging Center

Strategies for Shared Research Resources for Enhancing Research Sustainability: Communicating Between Stakeholders and Managing Expectations to Maximize Value and Impact

Research for the Future: An Overview of the FASEB Shared Research Resources Task Force’s Finding and Recommendations

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