Establishing a Satellite Transfusion Service Within an Academic Medical Center

Murphy, Colin; Lim, Albert Yick Hou; Chua, Lee Chuan; Shan, Hua; Goodnough, Lawrence T.; Virk, Mrigender

doi:10.1093/ajcp/aqaa018

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…Another problem with blood transporting is the manpower cost [ 30 ]. In a study quantifying the cost of patient care with transfusion-dependent thalassemia, the procedure costs (55%) were higher than the blood costs (40%) [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

Electronic transfusion consent and blood delivering pattern improve the management of blood bank in China

Lei

Zhang

Hao

et al. 2022

BMC Health Serv Res

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Background The aim of this study was to improve the blood transfusion treatment consent accuracy, simplify the verification process, prolong the temperature control time before the blood transfusion, and save the blood transportation labor cost. Methods We designed the blood transfusion consent electronic signing process, which can generate personalized the text content and can automatically check the filling accuracy. The signal can be transmitted to the blood transfusion management system (TMS) to relieving the blood distribution. For blood delivering pattern, we established the blood transport center, recruited full-time nurses and used temperature-controlled blood transfer boxes to deliver blood in batches on a regular basis. Results A quarterly data analysis of blood transfusion quality showed a 100% blood transfusion consent accuracy after an electronic signing process was implemented. The average confirmation time savings between the electronic content and paper content was 26 min for the Department of Emergency (estimated difference 95% CI = 26 (20 to 36), p < 0.05). The blood delivering pattern reduced the time for each unit by leaving the average temperature control by 7.24 min (estimated difference 95% CI = 7.24 (6.92 to 7.56), p < 0.05). Furthermore, $3.67 was saved for the blood transportation labor cost for each unit as well. Conclusion Blood transfusion consent electronic signing process not only ensures the accuracy, but also saves the verification time. Moreover, the blood delivering pattern prolongs the blood temperature control time and saves blood transportation labor costs. Thus, these two improvements could enhance transfusion management.

show abstract

Section: Discussionmentioning

confidence: 99%

Electronic transfusion consent and blood delivering pattern improve the management of blood bank in China

Lei

Zhang

Hao

et al. 2022

BMC Health Serv Res

View full text Add to dashboard Cite

show abstract

“…Another problem with blood transporting is the cost of manpower [29]. In a study quantifying the cost of care in patients with transfusion-dependent thalassemia, procedure costs (55%) were higher than blood costs (40%) [30].…”

Section: Discussionmentioning

confidence: 99%

Electronic transfusion consent and blood delivering pattern improve the management of blood bank in China

Lei

Zhang²,

Hao

et al. 2022

Preprint

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Background The aim of this study was to improve the accuracy of blood transfusion treatment consent, simplify the verification process, prolong the temperature control time before blood transfusion, and save the labor cost of blood transportation. Methods We designed the electronic signing process of blood transfusion consent, which can generate personalized text content and automatically check the accuracy of filling. The signal can be transmitted to the blood transfusion management system (TMS) to relieve the blood distribution. For blood delivering, we established the blood transport center, recruited full-time nurses and used temperature-controlled blood transfer boxes to deliver blood in batches on a regular basis. Results Quarterly analysis of blood transfusion quality data showed that the accuracy of blood transfusion consent was 100% after electronic consent process implemented. The average savings of confirmation time between electronic content and papery content was 26min for Department of Emergency (Estimated Difference (95% CI) = 26 (20 to 36), p< 0.05). The pattern of blood delivering reduced the time for each unit of leaving temperature control by 7.24min on average (Estimated Difference (95% CI) = 7.24 (6.92 to 7.56), p< 0.05), and saved $3.67 of labor cost for each unit as well. Conclusion Electronic transfusion consent process not only ensures the accuracy, but also saves the verification time. Moreover, the blood delivering pattern prolongs the temperature control time of blood, and saves labor costs. These two improvements could enhance transfusion management.

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Reaktionsmuster der lokoregionären Lymphknoten im Abflussgebiet von COVID-19-Lungen

et al. 2021

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Zusammenfassung Hintergrund Eine dysregulierte Immunantwort, z. B. in der Form eines Zytokinsturmes, einer Störung des Immunglobulinklassenwechsels, eines sog. antikörpervermitteltem Enhancements oder einer aberranten Antigenpräsentation wurde bereits in schweren Krankheitsverläufen von COVID-19 beschrieben. Ziel der Arbeit Zur Charakterisierung der COVID-19-Immunantwort wurde die Histomorphologie der Lymphknoten des pulmonalen Abflussgebietes untersucht. Material und Methoden Regionale Lymphknoten des pulmonalen Abflussgebiets wurden bei COVID-19-Autopsien asserviert (n = 20). Deren Histomorphologie, SARS-CoV-2-qRT-PCR sowie Genexpressionsanalysen von gängigen Genen der Immunantwort wurden berücksichtigt. Ergebnisse Histologisch zeigten sich ein mäßig- bis schwergradiges Ödem mit Kapillarostase, eine erhöhte Anzahl von extrafollikulären Plasmablasten, milde bis mäßige Plasmazytose, vermehrte CD8+-T-Zellen und CD11c/CD68+-Histiozyten mit Hämophagozytoseaktivität. Von 20 Fällen wiesen 18 hypoplastische oder fehlende Keimzentren sowie eine Verminderung der follikulären dendritischen Zellen und follikulären T‑Helferzellen auf. In 14 von 20 Fällen war der qRT-PCR-Nachweis von SARS-CoV‑2 positiv, jedoch zeigte sich nur bei einem einzigen Fall eine immunhistochemische Positivität für SARS-CoV-2-N-Antigene in Sinushistiozyten. In Genexpressionsanalysen war eine erhöhte Expression von STAT1, CD163, Granzym B, CD8A, MZB1 und PAK1, neben CXCL9 zu beobachten. Diskussion Die Befunde in den Lymphknoten deuten auf eine dysregulierte Immunantwort bei schweren COVID-19-Krankheitsverläufen hin. Insbesondere impliziert das Ausbleiben der Keimzentrumsreaktion und die vermehrte Präsenz von Plasmablasten eine nur transiente B‑Zellreaktion, welche die Entwicklung einer Langzeitimmunität infrage stellt.

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Establishing a Satellite Transfusion Service Within an Academic Medical Center

Cited by 4 publications

References 13 publications

Electronic transfusion consent and blood delivering pattern improve the management of blood bank in China

Electronic transfusion consent and blood delivering pattern improve the management of blood bank in China

Electronic transfusion consent and blood delivering pattern improve the management of blood bank in China

Reaktionsmuster der lokoregionären Lymphknoten im Abflussgebiet von COVID-19-Lungen

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