Establishment of a murine monoclonal antibody against human clear cell carcinoma and analysis of the corresponding antigen

Serum levels and biochemical characteristics of human ovarian carcinoma-associated antigen defined by murine monoclonal antibody, CF511

“…A large number of monoclonal antibodies (Mabs) against ovarian carcinoma have been produced using hybridoma technology, mainly by immunising mice with cancer cell lines or their extracts, in an attempt to identify tumour-specific or tissue-specific markers (Sakakibara et al, 1988;Nakagawa et al, 1987;Miotti et al, 1985Miotti et al, , 1987Mattes et al, 1984Mattes et al, , 1987Tsuji et al, 1985;Tagliabue et al, 1985;Croghan et al, 1984;Bhattacharya et al, 1982;Bast et al, 1981). As yet, however, none of the antigens identified appears to be tumour-specific.…”