Establishment of a prognosis predictive model for liver cancer based on expression of genes involved in the ubiquitin-proteasome pathway
Hua Li,
Yi-Po Ma,
Hai-Long Wang
et al.
Abstract:BACKGROUND
The ubiquitin-proteasome pathway (UPP) has been proven to play important roles in cancer.
AIM
To investigate the prognostic significance of genes involved in the UPP and develop a predictive model for liver cancer based on the expression of these genes.
METHODS
In this study, UPP-related E1, E2, E3, deubiquitylating enzyme, and proteasome gene sets were obtained from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, aiming to screen the pr… Show more
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