2024
DOI: 10.3390/cells13110992
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Establishment of Canine Oral Mucosal Melanoma Cell Lines and Their Xenogeneic Animal Models

Shumin Li,
Zichen Liu,
Jinbao Lv
et al.

Abstract: Canine oral melanoma is the most prevalent malignant tumor in dogs and has a poor prognosis due to its high aggressiveness and high metastasis and recurrence rates. More research is needed into its treatment and to understand its pathogenic factors. In this study, we isolated a canine oral mucosal melanoma (COMM) cell line designated as COMM6605, which has now been stably passaged for more than 100 generations, with a successful monoclonal assay and a cell multiplication time of 22.2 h. G-banded karyotype anal… Show more

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