Establishment of diagnostic criteria for feline nonflea‐induced hypersensitivity dermatitis

Favrot, Claude; Steffan, Jean; Seewald, Wolfgang; Hobi, Stefan; Линек, Моника; Marignac, Geneviève; Olivry, Thierry; Beco, Luc; Nett, Claudia; Fontaine, Jacques; Roosje, Petra; Bergvall, Kerstin; Белова, С А; Koebrich, Stefanie; Pin, Didier; Kovalik, Marcel; Meury, Sabrina; Wilhelm, Sylvia

doi:10.1111/j.1365-3164.2011.01006.x

Cited by 61 publications

(96 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…No significant differences in hypersensitivity skin disorders between PPG and TAG cats were observed. It should be noted that, although the incidence in the present study was low, it might still be overestimated since diagnoses were mostly suspected rather than based on exclusion of other pruritic viral, fungal, bacterial or parasitic diseases (Hobi and others 2011, Favrot and others 2012). Based on the current findings, it seems unlikely that age of gonadectomy is associated with feline hypersensitivity skin disorders.…”

Section: Discussionmentioning

confidence: 60%

Relationship between age at gonadectomy and health problems in kittens adopted from shelters

et al. 2015

View full text Add to dashboard Cite

Prepubertal gonadectomy (PPG) is promoted as a way of managing overpopulation in cats, but concerns about PPG and potential health issues still exist. The objective of the present study was to evaluate short-term and long-term health problems in cats subjected to PPG in comparison to gonadectomy at traditional age (TAG). In a prospective clinical trial, 800 shelter kittens aged between approximately 8 weeks and 12 weeks were recruited before adoption and randomly assigned to either the PPG group (gonadectomy performed immediately) or the TAG group (gonadectomy delayed until six months to eight months of age). Short-term health issues included mortality between when kittens arrived at the clinic and up to seven days after they returned to the shelter, as well as the occurrence of various other health issues arising in the first month following adoption. Kittens were followed-up until 24 months of age specifically for feline lower urinary tract disease, urethral obstruction (male cats), lameness, fractures and hypersensitivity disorders with dermatological presentation. In the short term, there were no significant differences between health problems in PPG and TAG kittens. Similarly, no significant differences were observed between treatment groups in terms of the type or number of health issues in the long term. In conclusion, there are no health-related contraindications to advocating PPG strategies in shelter cats. Ideally, PPG should be performed at the shelter facility itself as long as excellent infectious disease control and postoperative clinical observation before adoption are guaranteed

show abstract

Section: Discussionmentioning

confidence: 60%

Relationship between age at gonadectomy and health problems in kittens adopted from shelters

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Neither intradermal nor serological testing procedures are used for the diagnosis of FAD, but only for identifying allergens that may be important in avoidance and ASIT protocols. It is absolutely critical to remember that the diagnosis of FAD is achieved by the recognition of compatible historical and clinical findings, and by ruling out all disorders that mimic FAD 7,15,26,38) .…”

Section: Discussionmentioning

confidence: 99%

“…2. The exclusion of other conditions that mimic the clinical aspects of AD 7,15,26) . This was accomplished by skin scrapings, flea combings, trichography, cytology, skin biopsy, novel diet trials, and response to therapy as appropriate to each case 26) .…”

Section: Methodsmentioning

confidence: 99%

“…These reaction patterns are reportedly seen in various combinations in any given cat. The diagnosis of FAD is based on compatible historical and clinical findings, and the ruling out of all conditions that can produce similar clinical reaction patterns 7,15,26) . Management of FAD includes allergen avoidance, allergen-specific immunotherapy, various anti-inflammatory medications, and combinations of these 3,26,38,42) .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Feline Atopic Dermatitis: A Retrospective Study of 194 Cases (1988^|^ndash;2003)

Scott

Miller

2013

Jpn J Vet Dermatol

View full text Add to dashboard Cite

Atopic dermatitis was diagnosed in 13.8% of the feline dermatology cases and 0.9% of all cats examined over a 15-year period. No age or sex predilection was found, but Abyssinians, Himalayans, and Persians were over-represented. Clinical signs were nonseasonal in 62.4% of the cats. Cutaneous reaction patterns -in descending order of prevalence -included initially lesionless symmetrical pruritus (especially face, ears, and neck), self-induced hair loss (especially abdomen, back, and legs), miliary dermatitis (especially back and neck), and eosinophilic granuloma complex (especially lips, abdomen, and medial thighs). Multiple cutaneous reaction patterns were present in 36.2% of the cats. Secondary bacterial or yeast infections occurred in 18.6% and 6.6%, respectively, of the cats. Only 4.5% of the cats had concurrent food allergy, and none had flea-bite hypersensitivity. Medical management with systemic glucocorticoids, antihistamines, omega-6/ omega-3 fatty acids, allergen-specific immunotherapy, or combinations of these provided satisfactory control of clinical signs for the majority of affected cats.

show abstract

“…Finally, environmental causes of hypersensitivity can also induce FEGC. Also named atopic dermatitis or ‘non-flea non-food-induced hypersensitivity’, 8,9 this condition is diagnosed after exclusion of FAD and CAFR. As allergic tests are not validated in cats and often difficult to interpret they were not performed in these cases.…”

Section: Case Reportmentioning

confidence: 99%

Feline familial pedal eosinophilic dermatosis in two littermates

Pressanti¹,

Cadiergues²

2015

Journal of Feline Medicine and Surgery Open Reports

View full text Add to dashboard Cite

In cats, the most common eosinophilic dermatoses are feline miliary dermatitis and eosinophilic granuloma complex. The most commonly identified underlying cause is a hypersensitivity reaction. Few cases of familial forms of eosinophilic dermatoses are reported in the literature. Two young adult cats from the same litter presented 2 years apart with a severe and chronic fluid or tissue infiltration of the distal part of several limbs. Lesions started on the forelegs and developed on the other limbs. Cytological and histopathological examinations showed lesions consistent with an atypical form of feline eosinophilic dermatosis associated with secondary bacterial infection. In both cats, antibiotics combined with immunosuppressive treatment partially improved the lesions, which continued to progress on a waxing and waning course, even in the absence of treatment. Allergy work-up did not permit the identification of an underlying allergic triggering factor. The severity of the lesions, the unusual presentation and the unsatisfactory response to immunosuppressive therapy in two feline littermates suggested a genetic form of eosinophilic dermatosis.

show abstract

Establishment of diagnostic criteria for feline nonflea‐induced hypersensitivity dermatitis

Cited by 61 publications

References 7 publications

Relationship between age at gonadectomy and health problems in kittens adopted from shelters

Relationship between age at gonadectomy and health problems in kittens adopted from shelters

Feline Atopic Dermatitis: A Retrospective Study of 194 Cases (1988^|^ndash;2003)

Feline familial pedal eosinophilic dermatosis in two littermates

Contact Info

Product

Resources

About