Estimate and reporting of longevity for cardiac implantable electronic devices: a proposal for standardized criteria

Censi, Federica; Mattei, Eugenio; Ricci, Renato Pietro; Berisso, Massimo Zoni; Landolina, Maurizio; Boriani, Giuseppe

doi:10.1080/17434440.2021.2013199

Expert Review of Medical Devices

2021

DOI: 10.1080/17434440.2021.2013199

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Estimate and reporting of longevity for cardiac implantable electronic devices: a proposal for standardized criteria

Federica Censi¹,

Eugenio Mattei²,

Renato Pietro Ricci³

et al.

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2024

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Systematic review and meta-analysis on the impact on outcomes of device algorithms for minimizing right ventricular pacing

Mei,

Imberti,

Vitolo

et al. 2024

Europace

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Background Physiological activation of the heart using algorithms to minimize right ventricular pacing (RVPm) may be an effective strategy to reduce adverse events in patients requiring anti-bradycardia therapies. This systematic review and meta-analysis aimed to evaluate current evidence on clinical outcomes for patients treated with RVPm algorithms compared to dual chamber pacing (DDD). Methods and results We conducted a systematic search of the PubMed database. The predefined endpoints were the occurrence of persistent/permanent atrial fibrillation (PerAF), cardiovascular (CV) hospitalization, all-cause death, and adverse symptoms. We also aimed to explore the differential effects of algorithms in studies enrolling a high percentage of atrioventricular block (AVB) patients. Eight studies (7229 patients) were included in the analysis. Compared to DDD-pacing, patients using RVPm algorithms showed a lower risk of PerAF (Odds Ratio [OR] 0.74, 95% confidence interval [CI] 0.57-0.97) and CV hospitalization (OR 0.77, 95% CI 0.61-0.97). No significant difference was found for all-cause death (OR 1.01, 95% CI 0.78-1.30) or adverse symptoms (OR 1.03, 95% CI 0.81-1.29). No significant interaction was found between the use of the RVPm strategy and studies enrolling a high percentage of AVB patients. The pooled mean RVP percentage for RVPm algorithms was 7.96% (95% CI 3.13-20.25), as compared with 45.11% (95% CI 26.64-76.38) of DDD-pacing. Conclusion Algorithms for RVPm may be effective in reducing the risk of PerAF and CV hospitalization in patients requiring anti-bradycardia therapies, without an increased risk of adverse symptoms. These results are also consistent for studies enrolling a high percentage of AVB patients.

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Systematic review and meta-analysis on the impact on outcomes of device algorithms for minimizing right ventricular pacing

Mei,

Imberti,

Vitolo

et al. 2024

Europace

View full text Add to dashboard Cite

show abstract

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Estimate and reporting of longevity for cardiac implantable electronic devices: a proposal for standardized criteria

Cited by 1 publication

References 34 publications

Systematic review and meta-analysis on the impact on outcomes of device algorithms for minimizing right ventricular pacing

Systematic review and meta-analysis on the impact on outcomes of device algorithms for minimizing right ventricular pacing

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