We present the line broadening and self broadening coefficients of the water isotopologue HD 16 O and study their dependence on quantum numbers up to J = 50 for P , Q , and R branches. Three calculation techniques have been used: the analytical model in the case of known quantum transition identification in normal modes; the JJ' dependence in the case when only J and level symmetry are known, and the semi empirical calculation technique for 50 ≥ J > 15.The derived regularities for the broadening coefficients of water vapor lines allow accurate calculation of HD 16 O spectra including millions of weak lines from the VTT line list (Voronin, Tennyson, and Tolchenov).