Estimated breast cancer risk and screening outcomes among premenopausal women with non-cyclic mastalgia

Abstract

Estimated breast cancer risk and screening outcomes among premenopausal women with non-cyclic mastalgiaSzacowane ryzyko raka sutka oraz wyniki badań skriningowych u przedmenopauzalnych kobiet z niecykliczną mastalgią p=0.0002; p=0.002; Gail lifetime risk: 8.98 ± 3.6% vs. 9.6 ± 3.9%, p=0.015; p=0.045). Radiological and clinical outcomes were comparable between the groups. Material and methods: 112 premenopausal women with non-cyclic breast pain and 182 control women who presented for prophylactic examination were screened with mammography and ultrasound. Breast cancer risk estimated with the Gail and Tyrer-Cuzick models along with screening outcomes were compared between the groups. Results: Premenopausal patients with mastalgia had lower estimated breast cancer risk than controls. The difference was observed with both the Gail and Tyrer-Cuzick models Conclusions:Breast pain was associated with lower estimated breast cancer risk but had no effect on screening outcomes in the study population.