Estimated effect of COVID‐19 lockdown on melanoma thickness and prognosis: a rate of growth model

Tejera‐Vaquerizo, Antonio; Nagore, Eduardo

doi:10.1111/jdv.16555

Cited by 43 publications

(59 citation statements)

References 13 publications

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“…6 Tejero-Vasaquez and Nagore developed a rate of growth model to estimate the effect of COVID-19 lockdown on melanoma thickness and prognosis. 7 They randomly selected 1000 melanomas with a known rate of growth from a database and the tumors were classified according to thickness based on the melanoma staging criteria of the American Joint Committee on Cancer. For each case, a rate of growth was used to predict tumor thickness after a diagnostic delay of 1 to 3 months.…”

Section: Melanoma Diagnosis and Surgery In The Era Of Covid-19mentioning

confidence: 99%

Melanoma and COVID ‐19: A narrative review focused on treatment

Elmas

Demirbaş

Düzayak

et al. 2020

Dermatologic Therapy

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Melanoma is the most severe form of skin cancer and its incidence has increased over the past few decades. COVID-19 pandemic affected the diagnosis and management of many diseases including melanoma. In this study, we aimed to provide a review focused on the diagnosis and management of melanoma in the era of COVID-19. A comprehensive search was conducted on PubMed, Web of Science, and Google Scholar databases using the keywords "melanoma," "coronavirus," "COVID 19," and "SARS-CoV-2." The relevant guidelines published by the European Society for Medical Oncology and the National Comprehensive Cancer Network were also included. The current guidelines recommend that surgical interventions for new diagnosis of invasive primary melanoma, patients with postoperative complications, wide resection and sentinel lymph node biopsy for newly diagnosed T3-T4 melanoma, and planned surgical procedures for patients in neo-adjuvant trials should be prioritized. Surgical treatment of T3/T4 melanomas should be prioritized over T1/T2 melanomas except for any melanoma in which large clinical residual lesion is visible. Adjuvant therapies can be postponed for up to 12 weeks depending on the local center circumstances. PD-1 inhibitor monotherapy is recommended for patients starting immunologic therapy. Combination immunotherapy is still considered suitable for patients with higher-risk disease. Encorafenib and binimetinib should be prioritized for patients requiring BRAF-targeted therapy due to the lower chance of symptoms mimicking COVID-19 infection.

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Section: Melanoma Diagnosis and Surgery In The Era Of Covid-19mentioning

confidence: 99%

Melanoma and COVID ‐19: A narrative review focused on treatment

Elmas

Demirbaş

Düzayak

et al. 2020

Dermatologic Therapy

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“…This measure had to prevent non-COVID-19 patients from being infected with SARS-CoV-2. Although this measure was supported by the majority of the medical staff, critical voices put forward that the collateral damage caused by this health care delay might transcend the COVID-19-related morbidity and mortality [ 11 , 12 , 13 ]. The HEP lasted for 7 weeks and was abrogated on May 4, 2020.…”

Section: Introductionmentioning

confidence: 99%

The Impact of the COVID-19 Pandemic and the Associated Belgian Governmental Measures on Cancer Screening, Surgical Pathology and Cytopathology

et al. 2020

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Introduction The severe acute respiratory syndrome coronavirus 2 caused a pandemic of coronavirus disease 2019 (COVID-19). Unprecedented public health actions were introduced, including social distancing, travel restrictions and quarantine. The Belgian government announced a national emergency plan, thereby postponing all non-urgent medical consultations and operations. This report analyses the impact of these measures on cancer screening, through assessment of the workload of a laboratory for histopathology and cytopathology. Methods Data on monthly numbers of histological and cytological samples, immunohistochemistry and molecular tests were extracted from the laboratory information management system. Results The global histopathological and cytological workload was substantially reduced. The impact on oncology-related surgical procedures was rather limited. The anti-COVID-19 measures significantly diminished all screening-related samples, such as colon biopsies, breast biopsies and cervical cytology, and strongly reduced the number of samples related to “functional” pathology, such as thyroidectomies and gastric biopsies. Conclusions Since many health care interventions are reflected in the workload of a pathology laboratory, this study enabled us to identify areas for “deconfinement” health care actions. Our findings indicate that various areas in medicine were affected, but the impact seemed largest for cancer screening. Health care professionals should assure that consultations related to cancer screening are postponed instead of cancelled.

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“…Tejera-Vaquerizo and colleagues recently estimated that diagnostic and treatment delays in patients with skin tumors could lead to thicker tumors, increased mortality, 3 and higher health care costs. 4 Seventy percent of the SCCs in our series were classified as high-risk, but this high proportion is probably related to the inclusion criteria. It is noteworthy that 5 patients did not seek care earlier because they were not worried about their lesion, indicating that some members of the population are still unaware of the importance of early skin cancer diagnosis and highlighting the important role that general practitioners and teledermatology have in the early detection of high-risk skin tumors.…”

mentioning

confidence: 77%