Estimated Levels of Environmental Contamination and Health Risk Assessment for Herbicides and Insecticides in Surface Water of Ceará, Brazil

Sousa, Anayla S.; Duaví, Wersângela C.; Cavalcante, Rivelino M.; Milhome, Maria Aparecida Liberato; Nascimento, Ronaldo F.

doi:10.1007/s00128-015-1686-2

Cited by 47 publications

(16 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The maximum allowable atrazine concentrations in drinking water range from 0.1 to 3 μg L −1 in most regions, particularly in Europe, Asia and America (Singh et al, 2018). A recent monitoring study of atrazine across the Ceará state in Brazil revealed mean atrazine concentrations of 7-15 μg L −1 in reservoir water (Sousa et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Effects of environmentally relevant sub-chronic atrazine concentrations on African clawed frog (Xenopus laevis) survival, growth and male gonad development

Rimayi

Odusanya²,

Weiss

et al. 2018

Aquatic Toxicology

View full text Add to dashboard Cite

Sub-chronic toxicity of environmentally relevant atrazine concentrations on exposed tadpoles and adult male African clawed frogs (Xenopus laevis) was evaluated in a quality controlled laboratory for 90 days. The aim of this study was to determine the effects of atrazine on the survival, growth and gonad development of African clawed frogs. After exposure of tadpoles to atrazine concentrations of 0 (control), 0.01, 200 and 500 μg L in water, mortality rates of 0, 0, 3.3 and 70% respectively were recorded for the 90 day exposure period. Morphometry showed significantly reduced tadpole mass in the 500 μg L atrazine exposed tadpoles (p < 0.05). Light microscopy on testes of adult frogs exposed to the same atrazine concentrations using hematoxylin and eosin (H&E) and Van Gieson staining techniques revealed gonadal atrophy, disruption of germ cell lines, seminiferous tubule structure damage and formation of extensive connective tissue around seminiferous tubules of frogs exposed to 200 μg L and 500 μg L atrazine concentrations. Ultrastructural analysis of the cellular organelles using transmission electron microscopy (TEM) revealed significant amounts of damaged mitochondria in testosterone producing Leydig cells as well as Sertoli cells. Biochemical analysis revealed reduced serum testosterone levels in adult frogs at all exposure levels as well as presence of six atrazine metabolites in frog serum and liver. The results indicate that atrazine concentrations greater than the calculated LC50 of 343.7 μg L cause significant mortality in tadpoles, while concentrations ≥200 μg L adversely affect reproductive health of adult frogs and development of tadpoles sub-chronically exposed to atrazine.

show abstract

Section: Introductionmentioning

confidence: 99%

Effects of environmentally relevant sub-chronic atrazine concentrations on African clawed frog (Xenopus laevis) survival, growth and male gonad development

Rimayi

Odusanya²,

Weiss

et al. 2018

Aquatic Toxicology

View full text Add to dashboard Cite

show abstract

“…Particularly in Brazilian rivers, the presence of ATZ has often registered at permitted levels (2 µg/L) established by the Brazilian National Council of the Environment (CONAMA) [ 4 - 7 ]. However, ATZ was found above this level in several hydrographic basins in different regions of Brazil, ranging from a concentration of 2.7 µg/L [ 8 ], 10.4 µg/L [ 9 ], and 15.0 µg/L [ 10 ] up to 18.9 µg/L [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Acute toxicity of commercial atrazine in Piaractus mesopotamicus: Histopathological, ultrastructural, molecular, and genotoxic evaluation

Paiva¹,

Delcorso²,

Matheus³

et al. 2017

Vet World

View full text Add to dashboard Cite

Aim:The aim of this work was to evaluate the sensitivity of Pacu fingerlings (Piaractus mesopotamicus) by measuring the effects of median lethal concentration (LC50) of atrazine (ATZ - 28.58 mg/L) after acute exposure (up to 96 h).Materials and Methods:The fish were exposed to the LC50 of ATZ for 96 h (28.58 mg/L) in a static system. During the experiment, the fingerlings were randomly distributed in four glass tanks (50 L) containing dechlorinated water. Four glass tanks were for the control group, and four were for the ATZ-exposed group (n=4 per glass tank), given a total number of 16 animals tested per group. The genotoxicity was evaluated by micronucleus (MN) test in erythrocytes from peripheral blood. Qualitative and semi-quantitative histopathological analyses, and also ultrastructural study, were applied in liver and kidney samples. Finally, the content of heat shock protein (Hsp70) in the liver was evaluated by the western blotting method.Results:The morphological alterations in the liver, which was associated with increased expression of Hsp70, included nuclear and cytoplasmic vacuolization, cytoplasmic hyaline inclusions, and necrosis. The kidney presented edema and tubular cell degeneration with cytoplasmic hyaline inclusion. The semi-quantitative histopathological analyses indicated that the liver was more sensitive than kidney to ATZ-induced damage. Ultrastructural analysis showed that ATZ caused membrane alterations in several organelles and increased the number of lysosomes in hepatocytes and kidney proximal tubular cells. Nevertheless, no significant difference was observed in MN frequency in erythrocytes comparing treated and control groups.,Conclusion:These results indicated that ATZ-induced damage to the kidney and liver function, ATZ at the concentration tested did not induce a significant difference in MN frequency in Pacu erythrocytes comparing treated and control groups, and also that Pacu fingerlings may be a good bioindicator for testing freshwater contamination.

show abstract

“…Studies of atrazine in aquatic ecosystems from different regions have shown values ranging from less than 0.001 up to 1000 µg·L -1 (Graymore et al, 2001;USGS, 2000;Battaglin et al, 2009;Sangchan et al, 2014;Botelho et al, 2015;Sousa et al, 2016;Fingler et al, 2017;Starr et al, 2017). Therefore, the results of the present study showed that atrazine, at environmentally relevant concentrations, is a contaminant capable of triggering the avoidance response in the fish P. reticulata.…”

Section: Discussionmentioning

confidence: 99%

Effects of aquatic contaminants on the habitat selection and spatial distribution in fish: a complementary approach to traditional ecotoxicological tests

Silva¹

View full text Add to dashboard Cite

Dedicatória Dedico este trabalho aos meus pais, Ângela e Iberê, e à minha esposa e filho, Verónica e Gael, sem os quais eu não teria a inspiração e forças necessárias para chegar onde cheguei! Dedico também ao meu tio Clemente Silva Vieira Filho (in memorian), um dos homems mais humildes e altruístas que já conheci! ~ vi ~ Epígrafe "Let me tell you something you already know. The world ain't all sunshine and rainbows. It's a very mean and nasty place and i don't care how tough you are it will beat you to your knees and keep you there permanently if you let it. You, me, or nobody is gonna hit as hard as life. But it ain't about how hard ya hit. It's about how hard you can get hit and keep moving forward. How much you can take and keep moving forward. That's how winning is done!" Rocky Balboa. Directed by: Sylvester Stallone. Hollywood (U.S.A.): MGM Studios / Columbia Pictures, 2007, DVD. ~ vii ~ Agradecimentos A Deus, ADONAI, por ser minha fonte de forças e energia! Aos meus pais Ângela e Iberê, os quais sempre me apoiaram em toda a minha trajetória. A minha esposa Verónica, minha amada e companheira! Ao meu filho Gael, um menino lindo, que veio trazer inspiração e forças para que eu continuasse lutando! A minha família do Brasil... Roberta, Rodrigo, João Victor, Rafa e Tio Ricardo: A presença de vocês é indispensável para mim! A minha família da Argentina: Os considero como irmãos de sangue! Aos meu querido orientador e co-orientadores: Marcelo Pompêo, Teresa Paiva e Cristiano Araújo, os quais possibilitaram meu crescimento como profissional, me apoiando em todas as decisões científicas e acadêmicas! Vocês foram o pilar de mais essa minha vitória! Aos colegas de pós-graduação do DEBIQ, especialmente ao Douglas, Rodrigo Marassi, Fernanda Sampaio, Patrícia, Lucas e Luiz. As minhas maravilhosas alunas de IC: Thaíse e Amanda. Vocês foram um apoio imprescindível para minhas pesquisas! À Lucinha, minha técnica favorita! Aos pesquisadores e companheiros que me auxiliaram na escrita de meus artigos: Rui Ribeiro (Portugal), Julio Cézar Lopez-Doval (Espanha), Fernanda França, M. Neto (apoio total na reta final) e a querida Sheila Cardoso-Silva.

show abstract

Estimated Levels of Environmental Contamination and Health Risk Assessment for Herbicides and Insecticides in Surface Water of Ceará, Brazil

Cited by 47 publications

References 28 publications

Effects of environmentally relevant sub-chronic atrazine concentrations on African clawed frog (Xenopus laevis) survival, growth and male gonad development

Effects of environmentally relevant sub-chronic atrazine concentrations on African clawed frog (Xenopus laevis) survival, growth and male gonad development

Acute toxicity of commercial atrazine in Piaractus mesopotamicus: Histopathological, ultrastructural, molecular, and genotoxic evaluation

Effects of aquatic contaminants on the habitat selection and spatial distribution in fish: a complementary approach to traditional ecotoxicological tests

Contact Info

Product

Resources

About